Results 121 to 130 of about 129,709 (348)

Brain endogenous feedback and degrees of consciousness

, 2014
We present a model able to account for the mechanisms supporting different degrees of consciousness. We support our proposal with recent evidence from brain morphology and physiology, which indicate that the central nervous system contains two parallel ...
Carrara-Augustenborg, Claudia, Pereira, Alfredo [UNESP]   +1 more
core  

The Role of Sentience in the Theory of Consciousness and Medical Practice

, 2021
In this target paper, I focus on the concept of sentience in relation to the theory of consciousness and to practice in the medical sciences, neurology, and psychiatry, regarding both diagnostics and therapy.
Pereira Jr, Alfredo [UNESP]
core  

Neurophysiological and behavioural responses to music therapy in vegetative and minimally conscious states [PDF]

, 2013
Assessment of awareness for those with disorders of consciousness (DOC) is a challenging undertaking, due to the complex presentation of the population, where misdiagnosis rates remain high.
J. eFachner, Magee, W. L., R. Palaniappan, W.L. eMagee, W. L. Magee, J. eTaborin, Palaniappan, Ramaswamy, Julian O’Kelly, Magee, Wendy L., Palaniappan, R., L. eJames, L. James, J. Fachner, R. ePalaniappan, J. Taborin, James, L., Taborin, J., Fachner, J., O'Kelly, Julian, O’Kelly, Julian, Julian eO'Kelly   +20 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Disorders of consciousness : clinical and ethical perspective [PDF]

, 2014
Disorders of consciousness are among the main consequences of severe brain injury. They are characterised by the disruption of the relationship between the quantitative (arousal, wakefulness) and the qualitative (awareness of the self and environment ...
Binder, Marek, Marcin Koculak, Urszula Górska, Brocka, Marta, Koculak, Marcin, Marek Binder, Górska, Urszula, Marta Brocka   +7 more
core   +1 more source

Spasticity Management in Disorders of Consciousness

Brain Sciences, 2017
Background: Spasticity is a motor disorder frequently encountered after a lesion involving the central nervous system. It is hypothesized to arise from an anarchic reorganization of the pyramidal and parapyramidal fibers and leads to hypertonia and ...
Géraldine Martens, Steven Laureys, Aurore Thibaut   +2 more
doaj   +1 more source

Comprehensive systematic review update summary: Disorders of consciousness

Neurology, 2018
Objective To update the 1995 American Academy of Neurology (AAN) practice parameter on persistent vegetative state and the 2002 case definition for the minimally conscious state (MCS) by reviewing the literature on the diagnosis, natural history ...
J. Giacino, D. Katz, N. Schiff, J. Whyte, E. Ashman, S. Ashwal, R. Barbano, F. Hammond, Steven Laureys, G. Ling, R. Nakase-Richardson, R. Seel, S. Yablon, Thomas S. D. Getchius, G. Gronseth, M. Armstrong   +15 more
semanticscholar   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source