Results 121 to 130 of about 990,174 (349)

New Insights from Unbiased Panel and Whole-Exome Sequencing in a Large Chinese Cohort with Disorders of Sex Development.

European Journal of Endocrinology, 2019
CONTEXT Diagnosis of non-chromosomal type disorders of sex development (DSD) has long been challenging. There is still no research on overview of a large Chinese DSD cohort.
Yufei Xu, Yirou Wang, Niu Li, R. Yao, Guoqiang Li, Juan Li, Yu Ding, Yao Chen, Xiaodong Huang, Yulin Chen, Yanrong Qing, Tingting Yu, Yongnian Shen, Xiumin Wang, Yiping Shen, Jian Wang   +15 more
semanticscholar   +1 more source

Pubertal maturation and affective symptoms in adolescence and adulthood: evidence from a prospective birth cohort [PDF]

, 2015
The higher prevalence of affective symptoms among women compared to men emerges in adolescence, and it has been associated with pubertal maturation. However, it remains unclear whether pubertal timing has long-term influences on affective symptoms. Using
Darya Gaysina, Diana Kuh, Hayward, Herva, Huerta, Li, Marcus Richards, O'Dea, Palacios, Rebecca Hardy, Silbereisen, Stattin, Talashek, Wing   +13 more
core   +1 more source

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
wiley   +1 more source

A clinical approach to diagnosis of ambiguous genitalia

Journal of Indian Association of Pediatric Surgeons, 2019
Disorders of sex development (DSD) are a sensitive and stressful condition for the family as well as the treating physician to deal with. The main issue in managing such cases is sex assignment.
Kashish Khanna, Shilpa Sharma, Devendra K Gupta   +2 more
doaj   +1 more source

Predictors of Psychosocial Distress in Parents of Young Children with Disorders of Sex Development.

Journal of Urology, 2019
PURPOSE To evaluate demographic, financial, and support predictors of distress for parents of young children with Disorders of Sex Development (DSD) including atypical genital development, and to characterize early parental experiences.
Megan N Perez, A. M. Delozier, C. Aston, P. Austin, L. Baskin, Yee-Ming Chan, E. Cheng, D. Diamond, A. Fried, S. Greenfield, T. Kolon, B. Kropp, Y. Lakshmanan, S. Meyer, T. Meyer, N. Nokoff, B. Palmer, A. Paradis, D. Poppas, Kristy J. Scott Reyes, J. Swartz, A. Tishelman, A. Wisniewski, C. Wolfe‐Christensen, E. Yerkes, L. Mullins   +25 more
semanticscholar   +1 more source

Evaluating the Effects of Bisphenols F and S with Respect to Bisphenol A on Primordial Germ Cell Migration in Zebrafish (Danio rerio) Embryos Using Immunofluorescence Microscopy [PDF]

, 2019
Primordial Germ Cell (PGC) migration occurs in early embryonic development and is highly conserved across taxa. PGC migration occurs within the first 24 hours post fertilization (hpf) in zebrafish, making the organism an efficient model for observing the
Freeman, Edward A., Roba, George, Safura, Siti Sarah   +2 more
core   +1 more source

Disorders of Sex Development - Ambiguous Genitalia

, 2016
Disorders of sex development (DSD) encompass a wide range of congenital conditions with diverse features and pathophysiology, which usually present in the newborn period or during adolescence (Ahmed et al., 2015), where the development of chromosomal ...
Davies, K, Davies, K
core   +2 more sources

Allergic fetal priming leads to developmental, behavioral and neurobiological changes in mice. [PDF]

, 2015
The state of the mother's immune system during pregnancy has an important role in fetal development and disruptions in the balance of this system are associated with a range of neurologic, neuropsychiatric and neurodevelopmental disorders ...
Ashwood, P, Careaga, M, Chang, C, Onore, CE, Schwartzer, JJ   +4 more
core   +2 more sources

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito   +13 more
wiley   +1 more source

Fertility Issues in Disorders of Sex Development

Endocrinology and Metabolism Clinics of North America, 2015
Fertility potential should be considered by the multidisciplinary team when addressing gender assignment, surgical management, and patient and family counselling of individuals with disorders of sex development. In 46,XY individuals, defects of gonadal differentiation or androgen or anti-Müllerian hormone synthesis or action result in incomplete or ...
Gabriela Guercio, Mariana Costanzo, Rodolfo Rey, Rodolfo Rey, Romina P Grinspon   +4 more
openaire   +4 more sources