Results 131 to 140 of about 990,174 (349)

Management framework paradigms for disorders of sex development

Archives of Endocrinology and Metabolism, 2015
Until 2005, questions regarding medical treatment and diagnostic information on Disorders of Sex Development (DSD) were not systematically discussed with both the patients and their families; however, the way these patients are currently treated have ...
Mariana Telles-Silveira, Felicia Knobloch, Claudio E. Kater   +2 more
doaj   +1 more source

Etiology and Clinical Presentation of Disorders of Sex Development in Kenyan Children and Adolescents

International Journal of Endocrinology, 2019
Objective The purpose of this study was to describe baseline data on etiological, clinical, laboratory, and management strategies in Kenyan children and adolescents with Disorders of Sex Development (DSD).
Prisca Amolo, P. Laigong, A. Omar, S. Drop   +3 more
semanticscholar   +1 more source

Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett, Karl Everett, Colleen J. Maxwell, Feng Zhu, Ayesha Asaf, Ping Li, Kyla A. McKay, Yinshan Zhao, Ruth Ann Marrie   +8 more
wiley   +1 more source

NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development

Genetics in Medicine, 2016
Purpose:We aimed to identify the genetic cause in a cohort of 11 unrelated cases and two sisters with 46,XX SRY-negative (ovo)testicular disorders of sex development (DSD).Methods:Whole-exome sequencing (n = 9), targeted resequencing (n = 4), and ...
D. Baetens, H. Stoop, F. Peelman, Anne-Laure Todeschini, Toon Rosseel, F. Coppieters, R. Veitia, L. Looijenga, E. de Baere, M. Cools   +9 more
semanticscholar   +1 more source

Sex assignment in conditions affecting sex development [PDF]

, 2017
The newborn infant with atypical genitalia presents a challenging clinical scenario and requires expert input. There have been appreciable advances in our knowledge of the underlying causes that may lead to a mere difference or a more serious disorder of
Ahmed, S. Faisal, Markosyan, Renata
core   +1 more source

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone, Alessandra Colamatteo, Teresa Micillo, Gianmarco Abbadessa, Silvia Garavelli, Clorinda Fusco, Claudia Russo, Francesco Perna, Federica Garziano, Claudia La Rocca, Maria Mottola, Giorgia Teresa Maniscalco, Simona Bonavita, Antonio Luca Spiezia, Alessia Castiello, Roberta Lanzillo, Vincenzo Brescia Morra, Claudio Procaccini, Paola de Candia, Giuseppe Matarese   +19 more
wiley   +1 more source

TO DETERMINE CUT OFF OF FERTILITY PROFILE OF PATIENTS WITH ANDROGEN INSENSITIVITY SYNDROME (AIS) AT DIFFERENT AGES IN PAKISTANI POPULATION

Pakistan Armed Forces Medical Journal, 2020
Objective: Current study was aimed to determine cut off value of fertility profile in patients with Androgen Insensitivity Syndrome (AIS) presented at different ages tertiary care hospital of Rawalpindi, Pakistan. Study Design: Cross sectional study.
Waqas Hanif, Naveed Asif, Muhammad Younas, Zujaja Hina Haroon, Qurat Ul Ain, Noreen .   +5 more
doaj  

Surgical and functional outcomes of sigmoid vaginoplasty among patients with variants of disorders of sex development

International Brazilian Journal of Urology, 2012
PURPOSE:To assess the use of sigmoid colon in vaginal reconstruction of some patients with disorders of sex development. MATERIALS AND METHODS: The study included 31 patients with disorders of sex development of various causes. All were reared as females.
A Nowier, M Esmat, RT Hamza
doaj   +1 more source

Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion, Mario Stanziano, Ludovico D'Incerti, Davide Sattin, Stefania Ferraro, Davide Rossi Sebastiano, Francesca Giulia Magnani, Alice Deruti, Davide Fedeli, Ludovico Minati, Francesca Epifani, Marina Grisoli, Matilde Leonardi, Maria Grazia Bruzzone, Anna Nigri, Cristina Rosazza   +15 more
wiley   +1 more source

46 XX karyotype during male fertility evaluation; case series and literature review

Asian Journal of Andrology, 2017
Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man′s fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype.
Ahmad Majzoub, Mohamed Arafa, Christopher Starks, Haitham Elbardisi, Sami Al Said, Edmund Sabanegh   +5 more
doaj   +1 more source