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Advances in genomic diagnosis of a large cohort of Egyptian patients with disorders of sex development

American Journal of Medical Genetics. Part A, 2021
Disorders/differences of sex development (DSD) comprise a group of congenital disorders that affect the genitourinary tract and usually involve the endocrine and reproductive system.
I. Mazen   +13 more
semanticscholar   +1 more source

Disorders of sex development

Revista Internacional de Andrología, 2013
Abstract Background Disorders of sex development (DSD), which has the possibility of the risk of life-threatening endocrinologic emergencies of the newborn, require a careful multidisciplinary approach. Objectives The aim of our study is to consolidate the proposed classification, evaluation and management of DSD.
ALAN, CABİR   +5 more
openaire   +5 more sources

Disorders of sex development

Current Opinion in Obstetrics & Gynecology, 2007
The current management of patients with intersex, now designated as disorders of sex development, is presented in the context of updated etiological and outcome data, refined surgical procedures and the need for a multidisciplinary approach.The recently published consensus statement, the primary publication cited herein, includes known genetic causes ...
Peter A. Lee, Zeina M. Nabhan
openaire   +3 more sources

Disorders of Sex Development

2010
Phenotypic sex results from the differentiation of internal ducts and external genitalia under the influence of hormones and other factors. When discordance occurs among three processes (chromosomal, gonadal, phenotypic sex determination), a disorder of sex development (DSD) is the result.
Justin H Davies   +2 more
openaire   +4 more sources

Disorders or Differences of Sex Development? Views of Affected Individuals on DSD Terminology

Journal of Sex Research, 2020
Over a decade ago, the participants at the International Consensus Conference on Intersex proposed Disorders of Sex Development (DSD) as an umbrella term for “congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is ...
Elena Bennecke   +9 more
semanticscholar   +1 more source

Survey of disorders of sex development in a large cohort of patients with diverse Mendelian phenotypes

American Journal of Medical Genetics. Part A, 2020
Disorders of sex development (DSD) are congenital conditions with atypical development of chromosomal, gonadal, or anatomical sex. The estimated incidence ranges from 1 in 4,500–5,500 for strictly defined “ambiguous genitalia” to 1 in 300 or higher when ...
Dalia Abualsaud   +3 more
semanticscholar   +1 more source

Patients' and Caregivers' Attitudes toward 'Disorders of Sex Development' Nomenclature.

Journal of Urology, 2020
OBJECTIVES Differences/disorders of sex development (DSD) medical terminology has been viewed negatively by some affected individuals. A clinical population of patients with DSD and their caregivers were surveyed regarding DSD nomenclature, hypothesizing
A. D'Oro   +17 more
semanticscholar   +1 more source

Disorders of Sex Development

2009
Disorders of sex development (DSD) are rare disorders occurring when there is a discordance between chromosomal, gonadal, or phenotypic sex. These occur in the presence of genetic mutations that affect one of the two major processes in sex development: sex determination or sex differentiation.
Eric Vilain, Valerie A. Arboleda
openaire   +6 more sources

Pediatric disorders of sex development

The Indian Journal of Pediatrics, 2009
The management of disorders of sexual differentiation (DSD) involves a multidisciplinary approach. The main aim of analysis was to study the phenotype-karyotype correlation in North Indian children with DSD. The records of pediatric DSD were retrieved and characteristics noted. Of total of 58 children, 43 (74.1%) and 10 (17.2%) were raised as males and
Ram Kumar Marwaha   +4 more
openaire   +3 more sources

Mental health outcomes among individuals with 46,XY disorders of sex development: A systematic review

Journal of Health Psychology, 2020
This review summarizes research on the mental health outcomes of genetic males with a disorder of sex development (46,XY DSD). Databases were systematically searched, yielding 19 studies included in this review.
Lisa M. Godfrey
semanticscholar   +1 more source

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