Results 41 to 50 of about 517,354 (173)
46,XY ovotesticular disorders of sex development: A therapeutic challenge
Pediatric Reports, 2017 46,XY ovotesticular disorder of sex development is extremely rare and indicates the presence of both testis and ovary in the same patient. Gender assignment in newborns represents a therapeutic challenge.
Maria-Grazia Scarpa +2 more
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Taiwanese Journal of Obstetrics & Gynecology, 2021 Objective: Sex chromosome mosaicism remains challenging in the study of disorders of sex development (DSD). Aneuploid cells in the developing gonad play a major role in sex determination. Therefore, it is necessary acknowledge their presence by different
Rosalba Sevilla-Montoya +6 more
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Cytogenomic description of a Mexican cohort with differences in sex development
Molecular CytogeneticsBackground Differences in Sex Development (DSD) is a heterogeneous group of congenital alterations that affect inner and/or outer primary sex characters. Although these conditions do not represent a mortality risk, they can have a severe psycho-emotional
Grecia C. Olivera-Bernal +9 more
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Transverse testicular ectopia with disorders of sex development
Indian Journal of Urology, 2012 Transverse testicular ectopia (TTE) is a rare congenital anomaly. Although TTE often coexists with abnormalities such as inguinal hernia and persistent Mullerian duct syndrome, disorders of sex development (DSD) in combination with TTE is extremely rare.
Katsuya Aoki +3 more
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Frontiers in Urology, 2023 IntroductionElective aspects of surgical management of pediatric differences of sex development (DSD) are associated with controversy. We examined North American pediatric urologist and endocrinologist perspectives regarding recommended and existing ...
Zoe K. Lapham +8 more
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Prenatal management of disorders of Sex development [PDF]
Journal of Pediatric Urology, 2012 Disorders of sex development (DSD) rarely present prenatally but, as they are very complex conditions, management should be directed by highly specialised medical teams to allow consideration of all aspects of diagnosis, treatment and ethical issues.
Katja P. Wolffenbuttel +4 more
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Unveiling the Significance of the Androgen Receptor Gene in Disorders of Sex Development
Advances in Human BiologyDisorders of sex development (DSD) encompass a range of congenital conditions where the development of chromosomal, gonadal or anatomical sex is atypical. There are many genes associated with DSD, and one of them is the androgen receptor (AR) gene, which
Ziske Maritska +5 more
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THE RISK FOR DEVELOPING TUMOR IN PATIENTS WITH GONADAL DYSGENESIS 46,XY
Бюллетень сибирской медицины, 2015 Disorders of sex development with Y chromosome material has been associated with a high risk for developing germ cell tumors such as gonadoblastoma or dysgerminoma.
O. Yu. Latyshev +5 more
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Management framework paradigms for disorders of sex development
Archives of Endocrinology and Metabolism, 2015 Until 2005, questions regarding medical treatment and diagnostic information on Disorders of Sex Development (DSD) were not systematically discussed with both the patients and their families; however, the way these patients are currently treated have ...
Mariana Telles-Silveira +2 more
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Performance of mutation pathogenicity prediction tools on missense variants associated with 46,XY differences of sex development [PDF]
ClinicsOBJECTIVES: Single nucleotide variants (SNVs) are the most common type of genetic variation among humans. High-throughput sequencing methods have recently characterized millions of SNVs in several thousand individuals from various populations, most of ...
Luciana R. Montenegro +4 more
doaj +2 more sources