Results 71 to 80 of about 298,251 (276)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Dominance Constraints for Risk Control of a VPP’s Optimal Bidding Strategy

IEEE Access
The Virtual Power Plant (VPP) serves as the primary form of participation for distributed power generation resources in electricity markets. Throughout this market engagement, uncertainties stemming from renewable energy sources and market prices present
Chaoyi Peng, Yubin He, Huijie Gu, Kaiting Lai, Xin Zhou, Huihong Luo, Cheng Dong, Xiaowen Lai   +7 more
doaj   +1 more source

Clark Praises Judicial System

, 1974
WILLIAMSBURG -- Former U.S. Supreme Court Justice Tom C. Clark said here Wednesday that he hoped there was no obstruction of justice on the part of President Nixon during the Watergate affair.
Richmond Times-Dispatch
core  

Dynamic Virtual Join Point Dispatch [PDF]

, 2006
Conceptually, join points are points in the execution of a program and advice is late-bound to them. We propose the notion of virtual join points that makes this concept explicit not only at a conceptual, but also at implementation level.
Bockisch, Christoph, Hauptmann, Michael, Mezini, Mira   +2 more
core   +3 more sources

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Reliable Communication in Distributed Photovoltaic Sensor Networks: A Large Language Model-Driven Approach

Sensors
Distributed photovoltaic (DPV) systems present a cost-effective and sustainable industrial energy solution, yet their reliable monitoring faces significant technological constraints.
Wu Dong, Xu Liu, Qing Liu, Guanghui Zhang, Ji Shi, Xun Zhao, Zhongming Lei, Wei Wang   +7 more
doaj   +1 more source

Darrell Due to Receive Law Medal

, 1967
WILLIAMSBURG -- Norris Darrell of New York, president of the American Law Institute since 1961, has been named the first recipient of the Marshall-Wythe School of Law Medallion.
Richmond Times-Dispatch
core  

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Deep learning-based GoogLeNet-embedded no-pooling dimension fully-connected network for short-term wind power prediction

Systems Science & Control Engineering
The dependence of wind power on the natural environment leads to volatility, which can cause hidden dangers to the safe and stable operation of the power grid.
Pingping Xie, Yang Liu, Qiuyu Lu, Xu Lin, Yinguo Yang, Xudong Hu   +5 more
doaj   +1 more source