Guideline Concordance and Documentation of Allopurinol Initiation Across Clinical Specialties: A Three-Year Retrospective Evaluation. [PDF]
Aboabat A +12 more
europepmc +1 more source
LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico +7 more
wiley +1 more source
Molecular Rectification: Mechanisms, Modulation Strategies, and Device Realization
This review focuses on molecular rectification, from its fundamental mechanisms and modulation strategies to device realization. It summarizes the theoretical framework, modulation strategies, fabrication techniques, characterization methods, and modeling and simulation of molecular rectifiers, while discussing challenges and future directions for ...
Junnan Guo +8 more
wiley +1 more source
Trends in First-Time Symptomatic Antidementia Drug Dispensations to Home-Dwelling People in Norway: A Nationwide Register-Based Study. [PDF]
Øvrebø TG +5 more
europepmc +1 more source
Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen +12 more
wiley +1 more source
New persistent opioid use after colorectal surgery in Sweden: A nationwide register-based cohort study. [PDF]
Gedda C +5 more
europepmc +1 more source
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao +7 more
wiley +1 more source
Temporal trends in the epidemiology of primary biliary cholangitis in the public healthcare system of Brazil: a large population-based study. [PDF]
Cançado GGL +10 more
europepmc +1 more source

