Results 161 to 170 of about 109,838 (310)

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Outdoor beverage dispensing. Khmer

, 2014
Title from PDF caption (viewed on January 18, 2023).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Dispensing Patterns of Influenza and Pneumococcal Vaccines in the Private Healthcare Sector in South Africa for 2017 to 2021: A Longitudinal Study. [PDF]

Pharmacoepidemiol Drug Saf
Truter I, Hugo J, Smith H, Bansal S, Vira A.   +4 more
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Trends and Gender Disparities in Medical Narcotics Utilization in South Korea: A Nationwide Population-Based Study, 2019-2023. [PDF]

Pharmacoepidemiol Drug Saf
Kim JH, Kim J, Kim S.
europepmc   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Multispectral UV Imaging on Capacitive CMOS Arrays Enabled by Solution‐Processed Metal‐Oxide Nanoparticles

Advanced Science, EarlyView.
Ultraviolet (UV) imagers are important for a variety of applications but often require dedicated semiconductor process flows. Here, a versatile capacitive CMOS platform is transformed into a visible‐blind, multispectral UV imager through post‐CMOS functionalization with solution‐processed metal‐oxide nanoparticles. The UV‐induced photodielectric effect
Suman Kundu, Tao Shen, Kai Betlem, Murali K. Ghatkesar, Peter G. Steeneken, Frans P. Widdershoven   +5 more
wiley   +1 more source

Photo‐Gated Corona Microfluidics

Advanced Science, EarlyView.
Photo‐gated corona microfluidics decouples optical programming from electric‐field actuation to enable reconfigurable manipulation on open, electrode‐pattern‐free surfaces. Near‐infrared irradiation locally melts paraffin, creating a reversible charge‐relaxation pathway that reconstructs the electric field.
Xiaxia Cui, Yiqing Liu, Xinyi Qiu, Manfei Liu, Biao Cheng, Yuan Zhou, Changguo Xue, Sheng Zhang, Xin Tang, Qiang Tang   +9 more
wiley   +1 more source

Drop‐Location‐Insensitive Droplet‐Based Electricity Generator Using Polydimethylsiloxane Slippery Covalently Attached Liquid Coatings

Advanced Science, EarlyView.
Drop‐location sensitivity remains a key barrier to practical droplet‐based electricity generators (DEGs). Here, a polydimethylsiloxane slippery covalently attached liquid (PDMS‐SCAL)‐coated interface promotes droplet sliding instead of splitting or bouncing, allowing stable electricity generation from randomly falling raindrops. The resulting PDMS‐SCAL‐
Jung Bin Yang, Donghyeon Yoo, Hideaki Teshima, Donghan Lee, Dongwhi Choi, Dong Rip Kim, Nenad Miljkovic   +6 more
wiley   +1 more source

Medication Dispensing Patterns Among Individuals With Serious Mental Illness Using a Remote Medication Dispensing and Adherence Monitoring Platform: Cohort Study. [PDF]

JMIR Ment Health
Unick G, Mattocks N, Yeung CY, Swenson N, Hopkins K, Manleigh C.   +5 more
europepmc   +1 more source