Results 221 to 230 of about 109,838 (310)

Long-Term Proton Pump Inhibitor Therapy Is Common Among Older Adults: An 8-Year Finnish Nationwide Register Study. [PDF]

Drugs Aging
Minkkinen L, Kari H, Nurminen F, Leppänen J, Koskinen H.   +4 more
europepmc   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

Thickness‐Gradient Liquid Metal Connectors for Seamless Electrophysiological Sensors

Advanced Science, EarlyView.
Thickness‐gradient liquid metal interfaces with elastomeric substrates enable seamless integration between ultrathin skin‐conformal electrodes and external interconnects. The mechanically compliant connector reduces interfacial mismatch and supports stable ECG/EMG monitoring under bending and motion.
Jinyoung Kim, Jaejun Lee, Christopher E. Tabor, Vladimir V. Tsukruk   +3 more
wiley   +1 more source

Trends in general practitioner dispensing of thickeners in the NHS England, 2019-24. [PDF]

PLoS One
McCurtin A, Collins L, Doody O, Kelly D, Lazenby-Paterson T, Lisiecka D, Smith A, O'Keeffe S, Swallow Perspectives, Advocacy & Research Collective.   +9 more
europepmc   +1 more source

Dispensing [PDF]

, 2020
openaire   +1 more source

A Scalable Droplet Microfluidic Platform That Overcomes Large‐Cell Constraints for Long‐Term Plant Cell Culture and Embryogenesis Analysis

Advanced Science, EarlyView.
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran, Fangchi Shao, Gregory Datto, Tathansh Joshi, Elizabeth Chatt, Yashar Bashirzadeh, Dan Stessman, Lai Wei, Kuangwen Hsieh, Hena Guo, Tza‐Huei Wang   +10 more
wiley   +1 more source

Antiviral Dispensing for Influenza Outpatients Younger Than 65 Years With Comorbidities: A Retrospective Cohort Study. [PDF]

Open Forum Infect Dis
Mirabito GG, Masalovich S, Uyeki TM, Reed C, Garg S, Adams K.   +5 more
europepmc   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

Territorial inequities in access to essential medicines for neglected tropical diseases in a decentralised European health system: a nationwide assessment in Spain. [PDF]

Infect Dis Poverty
Belhassen-García M, de la Calle-Prieto F, Del Moral Sánchez JM, Alonso-Sardón M, Ayuso-Garcia B, Blanco JR, Bustos Morell C, Campany-Herrero D, Carranza C, Ercilla Liceaga M, Garcia López-Hortelano M, García-Vázquez E, Garrido B, Hernandez Cabrera M, Ibero C, Illaro Uranga A, Jimenez Núñez C, Kortajarena Urkola X, Lapeña J, Llenas-García J, López-Vizcaíno A, Losada-Galvan I, Merino P, Moreno Á, Mulet AM, Navarro M, Pardo Lledías J, Perez-Molina JA, Periañez Parraga L, Picazo Sanchís G, Pozo Rosado L, Praena-Segovia J, Salas-Coronas J, Salvador F, Urda-Romacho J, Romay-Barja M.   +35 more
europepmc   +1 more source