Results 21 to 30 of about 22,201 (256)

Strategies implemented for accurate dispensing of an investigational new drug in a multi-site HIV prevention clinical trial

Contemporary Clinical Trials Communications, 2021
Safe practices for dispensing investigational product (IP) during clinical trials are not standardized and information in this regard is often limited.
Cindy Jacobson, Jayajothi Moodley, Aruna Bhoola, Rebecca Sakwa, Jeeva Moodley, Jasmin Sukdao, Nivriti Hurbans, Bhavna Maharaj, Anushka Naidoo, Melanie Maclachlan, Gift Chareka, Kudzai Hlahla, Mary Chadza   +12 more
doaj   +1 more source

An ocular medication dispensing error [PDF]

British Journal of Clinical Pharmacology, 2006
Drug treatment errors are common, with 20% of all medical negligence treatment claims arising from incorrect use of prescription drugs [1], mistakes being not only costly to individuals but also having a financial impact on the National Health Service in the United Kingdom. These errors can occur at several stages, including prescribing, transcription,
Eleanor Mein, Freda Sii, Peter Shah
openaire   +1 more source

Distribution of Dispensing Errors

Japanese Journal of Hospital Pharmacy, 1979
The distribution of dispensing errors occurring in hospital pharmacy was analyzed statistically. The sample distribution of the daily error rate (ie, rate of the number of dispensing errors detected daily to the number of prescriptions filled daily) could not be fully analyzed, because two peaks of the distribution were observed in the histogram.
YAMADA, TAIJU, FUJITA, HAJIME
openaire   +2 more sources

Dispensing Errors Detectable by Inspection (II)

Japanese Journal of Hospital Pharmacy, 1977
The number of dispensing errors occurring in hospital pharmacy and being detectable by inspection was studied by simple statistical method. Errors in calculation occurred most frequently. They often occurred 1) when new graduates are employed; 2) after vacation; 3) when places of vials of powder medicines are changed; 4) through carelessness; 5) in ...
YAMADA, TAIJU, FUJITA, HAJIME
openaire   +3 more sources

Dispensing processes impact apparent biological activity as determined by computational and statistical analyses. [PDF]

PLoS ONE, 2013
Dispensing and dilution processes may profoundly influence estimates of biological activity of compounds. Published data show Ephrin type-B receptor 4 IC50 values obtained via tip-based serial dilution and dispensing versus acoustic dispensing with ...
Sean Ekins, Joe Olechno, Antony J Williams   +2 more
doaj   +1 more source

Prevalence and contributing factors of dispensing errors in community pharmacies [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Dispensing errors pose a significant risk to patient safety and remain a primary concern in the practice of pharmacy. Aims: To assess the prevalence of dispensing errors and identify associated factors among community pharmacists in Jordan.
Anan S. Jarab, Walid Al-Qerem, Karem H. Alzoubi, Shrouq R. Abu Heshmeh, Joud Al-Momani, Tareq Mukattash, Yazid N. Al Hamarneh, Yousef Mimi, Maher Khdour   +8 more
doaj   +1 more source

Implementation of Medication-Related Technology and Its Impact on Pharmacy Workflow: Real-World Evidence Usability Study

Journal of Medical Internet Research
BackgroundMedication errors constitute a major contributor to patient harm, driving up health care costs and representing a preventable cause of medical incidents.
Wei-Ning Yu, Yih-Dih Cheng, Yu-Chi Hou, Yow-Wen Hsieh   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Medication errors and associated factors as perceived by nurses working at the national referral hospital in Bhutan

Bhutan Health Journal, 2022
Introduction: A common patient safety issue is medication error and this has remained a serious problem in hospital settings. Medication error occurs at any point of medication process: prescription, transcription, dispensing, and administration ...
Tshering Dema, Kencho Zangmo, Pema Dorji, Tshering Zangmo, Kezang Namgay, Kencho Wangdi, Sonam Jamtsho   +6 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source