Results 61 to 70 of about 933,240 (306)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Surface Chemistry of Silver Halide Microcrystals
Experimental techniques to study the surface properties of silver halide crystals in the ?m range, dispersed in gelatin, are discussed. The adsorption of sensitizing cyanine dyes and the properties of the adsorbed sensitizers on such silver ...
Rolf Steiger
doaj +2 more sources
Log-Normal or Over-Dispersed Poisson?
Although both over-dispersed Poisson and log-normal chain-ladder models are popular in claim reserving, it is not obvious when to choose which model. Yet, the two models are obviously different. While the over-dispersed Poisson model imposes the variance
Jonas Harnau
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
This study was dedicated to investigating the effects of clusters and dispersed randomly oriented wavy carbon nanotubes (CNTs) on the electrical conductivity of polymer nanocomposites.
Esmail Sharifzadeh +2 more
doaj +1 more source
Architecture of a Dispersed Gamification System for Tourist Attractions
The paper addresses the issues of implementing e-guide-based gamification systems for tourist attractions by proposing a dispersed gamification system architecture in which its respective functional aspects are handled by multiple web services with ...
Jakub Swacha
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
An early warning system to predict and mitigate wheat rust diseases in Ethiopia
Wheat rust diseases pose one of the greatest threats to global food security, including subsistence farmers in Ethiopia. The fungal spores transmitting wheat rust are dispersed by wind and can remain infectious after dispersal over long distances.
Clare Allen-Sader +14 more
doaj +1 more source
Fourier-domain low-coherence interferometry for light-scattering spectroscopy [PDF]
We present a novel method for obtaining depth-resolved spectra for determining scatterer size through elastic- scattering properties. Depth resolution is achieved with a white-light source in a Michelson interferometer with the mixed signal and reference
Izatt, Joseph A. +2 more
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

