Results 131 to 140 of about 2,741,856 (378)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Modification of Pinhole Apparatus for Identification and Classification of Dispersive Clay Soils

open access: yesJournal of Engineering and Sustainable Development, 2014
In this research, modification of the pinhole apparatus is made as required by the specification of the American Society for Testing and Materials (ASTM D4647 – 93)[3], which works on the basis that distilled water is passed horizontally under the ...
Mohammed Yousif Fattah   +2 more
doaj  

Acoustics aspects of technological process in the rock disintegration [PDF]

open access: yesActa Montanistica Slovaca, 2007
The paper describes some results of monitoring and aspects of the acoustic signal in the rock disintegration on the drillig stand of the Institute of Geotechnics, SAS in Košice.
Jozef Futó, František Krepelka
doaj  

The effect of the presence of obstacles on the emission dispersion emitted by a Bent chimney [PDF]

open access: yesFME Transactions, 2020
It is proposed to study numerically the dispersion of polluting emissions in turbulent conditions around a two-dimensional obstacle. The effect of the presence of obstacles on the flow from a Bent chimney is mainly addressed.
Zair Fida   +3 more
doaj  

The Dispersal Legend [PDF]

open access: yesThe Classical Review, 1913
n ...
openaire   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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