Results 171 to 180 of about 2,741,856 (378)
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
The effect of complete hepatectomy on the utilization by rats and rabbits of intravenously administered aqueous dispersions of carotene [PDF]
, 1956 N. A. Worker
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Revista de Investigaciones Marinas, 2014 El propósito de esta investigación fue estudiar la contaminación de un ecosistema de manglar impactado con hidrocarburos, en el sector centro sur de Cayo Santa María, Jardines del Rey, Cuba.
Jelvys Bermúdez Acosta +6 more
doaj
Non-Coherent Dispersion and the Formation of Fraunhofer Lines [PDF]
, 1936 Lyman Spitzer, A. S. Eddinǵton
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
OPTICAL DISPERSION OF CHINESE WOOD OIL AS AN INDEX OF PURITY [PDF]
, 1916 E. E. Ware
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Vergleichende Untersuchungen über Pfeilgift-Glykoside und andere Glykoside der Digitalisgruppe mit Hilfe des Brechungsexponenten und der Dispersion [PDF]
, 1905 M. Krause
openalex +1 more source