Results 31 to 40 of about 36,755 (264)
Strongly exactly n-resolvable spaces of arbitrarily large dispersion character
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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The paper presents a methodology that combines experimental measurements and mathematical-physics analyses to investigate the flow behavior in a nozzle-equipped aperture associated with the solution of its impact on electron beam dispersion in an ...
Pavla Šabacká +8 more
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The conductivity of the Li-containing Al-oxoferrite samples has been studied. Using Jonsher’s phenomenological approach, existence of 2 types of conductivity (electronic and ionic) in the above mentioned samples has been confirmed. Using Cole-Cole method,
I. M. Gasiuk +3 more
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The dramatically dispersive character of the traveling wave
Using optical coherence tomography (OCT) vibrometry we studied wave propagation by recording at multiple longitudinal positions in the gerbil and guinea pig cochlea. Our aims are to (1) fully portray the unusual dispersive character of the wave; (2) derive from these properties the underlying physics of the wave and the way it is regulated by ...
van der Heijden, Marcel +3 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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Dispersion characteristics of a nonlinear elastic metamaterial
We study wave dispersion in a one-dimensional nonlinear elastic metamaterial consisting of a thin rod with periodically attached local resonators. Our model is based on an exact finite-strain dispersion relation for a homogeneous solid, utilized in ...
R. Khajehtourian, M. I. Hussein
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Algorithm of the Rehabilitation of Patients with Pigmentary Glaucoma
Background. Irreversible changes in corneoscleral trabecula lead to persistent hydrodynamic disturbances not only in pigmentary glaucoma but also in pigmentary dispersion syndrome. In these cases isolated laser iridectomy cannot compensate ophthalmotonus
N. V. Volkova +3 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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