Results 121 to 130 of about 3,237,360 (342)

Inversion of Rayleigh wave dispersion curve based on beluga whale optimization algorithm

open access: yesContributions to Geophysics and Geodesy
Rayleigh wave exploration is a crucial technique in engineering site investigation for obtaining subsurface stratigraphic information. Inverting its dispersion curve can effectively reveal underground structures.
Fengjun WU   +4 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Application of SPAC method in dividing strata of the Quaternary strata

open access: yes河南理工大学学报. 自然科学版
The SPAC method is one of the most effective methods of extracting phase velocity from environmental noise. The calculation of S-wave velocity structure by the SPAC method has important scientific significance for studying velocity structure.ObjectivesTo
LI Baochun, SUN Shaohuai, LI Guoping
doaj   +1 more source

Measuring and Testing Advertising-Induced Rotation in the Demand Curve [PDF]

open access: yes
Advertising can rotate the demand curve if it changes the dispersion of consumers valuations. We provide an elasticity form measure of the advertising-induced demand curve rotation in five demand models and test for its presence in the U.S. non-alcoholic
Kaiser, Harry M.   +2 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Application of Microtremor Exploration in Loess Strata Division

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] During the deposition process, loess is significantly influenced by climatic conditions, exhibiting distinct layering alternations between loess and paleosols.
ZHANG Jihong   +3 more
doaj   +1 more source

Controlling for geographic dispersion when estimating the Japanese Phillips curve [PDF]

open access: yes
This paper argues that estimation of the Phillips curve for Japan should take account of the geographic dispersion of labor-market conditions. We find evidence that the relationship between wage inflation and the unemployment rate is convex.
Hiroshi Fujiki, Howard J. Wall
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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