Results 121 to 130 of about 807,113 (273)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Identification of broadband oscillation modal parameters in power systems based on IVMD-EDSNN

open access: yes电力工程技术
The frequent occurrence of broadband oscillation issues in "dual-high" power system poses a significant threat to its secure and stable operation. Extracting broadband oscillation modal information through identification techniques provides critical ...
Guoshuai XIE   +5 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

PV System Failures Diagnosis Based on Multiscale Dispersion Entropy. [PDF]

open access: yesEntropy (Basel), 2022
Lebreton C   +6 more
europepmc   +1 more source

Entropy Analysis of Univariate Biomedical Signals: Review and Comparison of Methods

open access: yes, 2022
Nonlinear techniques have found an increasing interest in the dynamical analysis of various kinds of systems. Among these techniques, entropy-based metrics have emerged as practical alternatives to classical techniques due to their wide applicability in ...
Escudero J.   +4 more
core  

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Fundamental Thermodynamic Aspects for the Effective Dispersion of Carbon Nanotubes and Improve Performance Grade of Bitumen

open access: yesApplied Sciences
The application of carbon nanotubes to enhance bitumen properties is relevant due to the need to increase the durability of asphalt concrete pavements and reduce maintenance costs. Key areas requiring further study include the processes during ultrasonic
Azariy Lapidus   +2 more
doaj   +1 more source

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