Results 101 to 110 of about 752,137 (289)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

On Schrödinger equations with modified dispersion [PDF]

open access: yesDynamics of Partial Differential Equations, 2011
Comment: 10 pages.
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Surface polaritons at the boundary of the bulk titanium – vacuum

open access: yesФизика волновых процессов и радиотехнические системы, 2013
The calculations of the real and imaginary part of complex dielectric constant of bulk Ti is produced by the first principles. Using the SIESTA program, the simulating of the interaction of light with substance is carried out.
Y.M. Aleksandrov, V.V. Yatsishen
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Influence of Secondary Currents on Solute Dispersion in Curved Open Channels

open access: yesJournal of Applied Mathematics, 2012
The dispersion coefficient tensor including off-diagonal components was introduced in the flow with secondary currents, which is called skewed shear flow dispersion (SSFD) coefficient tensor, in this paper.
Myung Eun Lee, Gunwoo Kim
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Online Correction of Dispersion Error in 2D Waveguide Meshes

open access: yes, 2000
An elastic ideal 2D propagation medium, i.e., a membrane, can be simulated by models discretizing the wave equation on the time-space grid (finite difference methods), or locally discretizing the solution of the wave equation (waveguide meshes).
Fontana, Federico, Rocchesso, Davide
core   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Two-Dimension Hydrodynamic Dispersion Equation with Seepage Velocity and Dispersion Coefficient as Function of Space and Time

open access: yesAbstract and Applied Analysis, 2013
The contamination through the geological formation cannot move and disperse with the same speed and dispersion coefficient, respectively, due to the variability of the geological formation.
Abdon Atangana, S. C. Oukouomi Noutchie
doaj   +1 more source

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