Results 211 to 220 of about 848,098 (285)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Mastering particle size analysis: lessons, challenges, and future directions from the FDA-CRCG workshop. [PDF]

AAPS Open
Xu X, Smith WC, Polli JE, Plavchak CL, Qin B, Wang Y, Holtgrewe N, Raney SG, O'Reilly Beringhs A, Yu YB, Taraban M, Krishnan V, Schwendeman A, Hammell DC, Clogston JD, Rawle AF, Grmaš J, Ayoub Y, Domnic B, Reddy RS, Duncan J, McGann M, Bodycomb J, Schuurmans CCL, Hermes M, Mehtala JG, Roy P, Lance K, Britten C, Park K, Beach D, Elmer M, Rodenhausen KB, Xu Z, Qu H, Wu KW, Korang-Yeboah M, Zou Y, Li J, Abuznait AH, Quinn C, Ethier A, Ip K, Dhamecha D, Li Q, Zhu D, Valapil R.   +46 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Is the P-wave dispersion a valuable tool in determining the atrial arrhythmia of newborn babies with sepsis? [PDF]

North Clin Istanb
Yilmaz FH, Arslan D, Ceylan C.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Polarization-Multiplexed Metalens Enables Switchable and Compact Chromatic Confocal Sensing with Dual-Mode Precision Control. [PDF]

Adv Sci (Weinh)
Zhao Z, Jiang Y, Lai T, Peng W, Hu Y, Chen S.   +5 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Distributed Data Classification with Coalition-Based Decision Trees and Decision Template Fusion. [PDF]

Entropy (Basel)
Kusztal K, Przybyła-Kasperek M.
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Theoretical View: Thermodynamics of the Saturation Dissolution of a Molecular (Solid) Dispersion of a Hydrophobic Molecule and Polymeric Surfactant in an Aqueous Solution. [PDF]

Int J Mol Sci
Poša M.
europepmc   +1 more source