Results 61 to 70 of about 1,213,794 (338)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Dispersion-managed soliton in a strong dispersion map limit

open access: yes, 2001
A dispersion-managed optical system with step-wise periodical variation of dispersion is studied in a strong dispersion map limit in the framework of path-averaged Gabitov-Turitsyn equation. The soliton solution is obtained by iterating the path-averaged
Ablowitz   +14 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Paraxial full-field cloaking [PDF]

open access: yes, 2015
We complete the `paraxial' (small-angle) ray optics cloaking formalism presented previously [Choi and Howell, Opt. Express 22, 29465 (2014)], by extending it to the full-field of light. Omnidirectionality is then the only relaxed parameter of what may be
Choi, Joseph S., Howell, John C.
core   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A Tunable Dispersion Waveguide Based on Graphene–Silicon Lateral Slot Geometric Structure

open access: yesIEEE Photonics Journal, 2017
The dispersion profiles of a hybrid graphene–silicon (HyGS) slot waveguide with trilayers of graphene are investigated in this paper. By tuning the bias voltage on graphene layer, the zero dispersion wavelengths (ZDW) of HyGS slot waveguide can be
Zhen Li   +4 more
doaj   +1 more source

Well-posedness of the mixed-fractional nonlinear Schrödinger equation on R2

open access: yesPartial Differential Equations in Applied Mathematics, 2022
We investigate the well-posedness theory of the 2-D fractional nonlinear Schrödinger equation (NLSE) with a mixed degree of derivatives. Motivated by models in optics and photonics where the light propagation is governed by non-quadratic, fractional, and
Brian Choi, Alejandro Aceves
doaj   +1 more source

Enhanced surface plasmon resonance absorption in metal-dielectric-metal layered microspheres

open access: yes, 2006
We present a theoretical study of the dispersion relation of surface plasmon resonances of mesoscopic metal-dielectric-metal microspheres. By analyzing the solutions to Maxwell's equations, we obtain a simple geometric condition for which the system ...
Cachorro   +15 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Cascaded chiral birefringent media enabled planar lens with programable chromatic aberration

open access: yesPhotoniX
Wavefront control is the fundamental requirement in optical informatics. Planar optics have drawn intensive attention due to the merits of compactness and light weight.
Dewei Zhang   +7 more
doaj   +1 more source

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