Results 101 to 110 of about 735,472 (273)

Label‐Free and Immobilization‐Free Protein‐Binding Assays by Ultraviolet Transient Absorption Microscopy

Advanced Science, EarlyView.
A femtosecond UV pump–probe microscope resolves binding‐induced changes in protein excited‐state dynamics and converts these intrinsic contrasts into an equilibrium affinity readout. By probing tryptophan responses directly in solution, the approach enables quantitative determination of dissociation constants without labeling or immobilization ...
Jianghao Shen, Qiangqiang Wang, Fan Wu, Yang Gao, Lu Lan, Pu Wang   +5 more
wiley   +1 more source

Optical qubit generation via atomic postselection in a Ramsey interferometer

, 2018
We propose a realizable experimental scheme to prepare a superposition of the vacuum and one-photon states using a typical cavity QED-setup. This is different from previous schemes, where the superposition state of the field is generated by resonant atom-
Orszag, Miguel, Oyarce, Felipe
core   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, EarlyView.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

Animal models of benign airway stenosis: Advances in construction techniques, evaluation systems, and perspectives

Animal Models and Experimental Medicine, EarlyView.
Currently, the animals commonly used to establish animal models of benign airway stenosis (BAS) include mice, rats, pigs, dogs, rabbits, and ferrets. The establishment methods involve one or a combination of two methods such as mechanical injury, tracheal cautery, cuff overpressure intubation, laser injury, and endoscopic silver nitrate cauterization ...
Wusheng Zhang, Yilin Chen, Chengcheng Yang, Yuchao Dong, Haidong Huang, Hui Shi, Chong Bai   +6 more
wiley   +1 more source

TEDI: the TripleSpec Exoplanet Discovery Instrument

, 2007
The TEDI (TripleSpec - Exoplanet Discovery Instrument) will be the first instrument fielded specifically for finding low-mass stellar companions. The instrument is a near infra-red interferometric spectrometer used as a radial velocimeter.
Edelstein, Jerry, Erskine, David J., Feuerstein, W. Michael, Gull, George E., Henderson, Charles, Herter, Terry, Lloyd, James P., Marckwordt, Mario, Muirhead, Phillip, Muterspaugh, Matthew Ward, Parshley, Stephen C., Wishnow, Ed   +11 more
core   +1 more source

Inter‐microscope comparability of dental microwear texture data obtained from different optical profilometers: Part II Deriving instrument‐specific correction equations for meta‐analyses using published data

The Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) has emerged as a valuable method for investigating the feeding ecology of vertebrates. Over the past decade, three‐dimensional topographic data from microscopic regions of tooth surfaces have been collected, and surface texture parameters have been published for both extant and fossil species.
Mugino O. Kubo, T. Kubo, Ellen Schulz‐Kornas, T. M. Kaiser, Daniela E. Winkler   +4 more
wiley   +1 more source

An overview of the mid-infrared spectro-interferometer MATISSE: science, concept, and current status

, 2016
MATISSE is the second-generation mid-infrared spectrograph and imager for the Very Large Telescope Interferometer (VLTI) at Paranal. This new interferometric instrument will allow significant advances by opening new avenues in various fundamental ...
Agocs, T., Allouche, F., Antonelli, P., Augereau, J. -C., Avila, G., Bailet, C., Beckmann, U., Behrend, J., Berger, J. -P., Berio, P., Bettonvil, F., Bourget, P., Brast, R., Bresson, Y., Bristow, P., Clausse, J. -M., Connot, C., Conzelmann, R., Cruzalebes, P., Csepany, G., Danchi, W. C., De Haan, M., Delbo, M., Dominik, C., Duc, T. Phan, Elswijk, E., Fantei, Y., Finger, G., Gabasch, A., Glindemann, A., Gonté, F., Graser, U., Guitton, F., Guniat, S., Haguenauer, P., Hanenburg, H., Heininger, M., Henning, T., Hofferbert, R., Hofmann, K. -H., Hogerheijde, M., Hron, J., Hummel, C., Isderda, J., Ives, D., Jaffe, W., Jakob, G., Jasko, A., Jolley, P., Kiraly, S., Kragt, J., Kroener, T., Kroes, G., Kuindersma, S., Labadie, L., Lagarde, S., Lanz, T., Laun, W., Lehmitz, M., Leinert, C., Lizon, J. -L., Lopez, B., Lucuix, C., Marcotto, A., Martinache, F., Martinot-Lagarde, G., Matter, A., Mauclert, N., Mehrgan, L., Meilland, A., Meisenheimer, K., Mellein, M., Menardi, S., Merand, A., Millour, F., Morel, S., Neumann, U., Nussbaum, E., Ottogalli, S., Palsa, R., Panduro, J., Pantin, E., Percheron, I., Petrov, R. G., Pott, J. -U., Pozna, E., Robbe-Dubois, S., Roelfsema, R., Rupprecht, G., Schertl, D., Schmidt, C., Schoeller, M., Schuil, M., Spang, A., stegmeier, J., ter Horst, R., Tromp, N., Vakili, F., Van Belle, G., van Boekel, R., van Duin, A., Vannier, M., Venema, L., Wagner, K., Weigelt, G., Woillez, J., Wolf, S.   +106 more
core   +2 more sources

Cross dual-microcomb dispersion interferometry ranging

Science Advances
Soliton microcombs offer unprecedented laser sources for high-precision ranging due to their merits of high repetition rate, excellent coherence, and compact size. However, high repetition rate limits the nonambiguity range (NAR) of ranging. Previous dual-comb–based methods can extend the NAR, but asynchronous measurement error (AME) is commonly ...
Yang Wang, Jindong Wang, Jingsheng Huang, Weiqiang Wang, Long Huang, Wen Shao, Minhui Cheng, Brent E. Little, Sai Tak Chu, Wei Zhao, Wenfu Zhang   +10 more
openaire   +1 more source

Odd- and Even-Order Dispersion Cancellation in Quantum Interferometry

Physical Review Letters, 2009
We describe a novel effect involving odd-order dispersion cancellation. We demonstrate that odd- and even-order dispersion cancellation may be obtained in different regions of a single quantum interferogram using frequency-anticorrelated entangled photons and a new type of quantum interferometer.
Minaeva, Olga, Bonato, Cristian, Saleh, Bahaa E. A., Simon, David S., Sergienko, Alexander V.   +4 more
openaire   +3 more sources

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

Biotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse, Fabian Schmitz, Janina Kilian, Jonas Austerjost, Lucas‐Nik Reger, Markus Kampmann   +5 more
wiley   +1 more source