Results 161 to 170 of about 735,472 (273)
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang +27 more
wiley +1 more source
ABSTRACT This study presents a comprehensive experimental evaluation of the reliability and thermal stability of a barium hydroxide octahydrate (BHO)‐based phase change material (PCM) with a phase change temperature of 78°C, focusing on supercooling suppression and corrosion resistance.
TaeHwan Song +6 more
wiley +1 more source
Externally Dispersed Interferometry For Terrestrial Exoplanet Detection
Terrestrial exoplanets are observationally challenging to detect and characterize. Compared to gas giant exoplanets, terrestrial exoplanets introduce significantly smaller radial velocity signals and transit depths on their host stars. The signals are larger for terrestrial exoplanets orbiting M-dwarf stars, which have lower masses and radii than Sun ...
openaire +1 more source
Surface Symphony: Orchestrating DPPC/DOPC Monolayer Behavior
Langmuir trough and atomic force microscopy reveals the physical nature of DPPC and DOPC mixed monolayers. ABSTRACT This study investigates the impact of environmental factors and lipid composition on the structural and morphological properties of DPPC/DOPC (1,2‐Dipalmitoyl‐sn‐glycero‐3‐phosphocholine/1,2‐dioleoyl‐sn‐glycero‐3‐phosphocholine ...
Wisnu Arfian A. Sudjarwo +1 more
wiley +1 more source
Look‐up table correction for beam hardening‐induced signal of clinical dark‐field chest radiographs
Abstract Background The microstructure of material at a μm$\,\umu\mathrm{m}$ length scale leads to ultra‐small‐angle scattering of X‐rays, which typically occurs, e.g., for lung tissue or some plastic foams. When using an interferometer, this effect alters the visibility of the fringe pattern, which can be detected and resolved by the detector.
Maximilian E. Lochschmidt +6 more
wiley +1 more source
Abstract Detergents provide essential membrane‐mimetic environments for studying G protein‐coupled receptors (GPCRs), but their molecular impact on receptor energetics remains incompletely understood. We combined ligand binding, thermostability measurements, and atomistic molecular dynamics to dissect detergent‐ versus ligand‐driven stabilization in a ...
James B. Bower +6 more
wiley +1 more source
Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings +6 more
wiley +1 more source
Magma Storage Below Sabancaya Volcano (Southern Peru) Imaged by Broadband Magnetotellurics
Abstract Sabancaya volcano is one of the most active volcanoes in the Central Andes. Its ongoing eruptive process is accompanied by large‐scale deformation, with activation of the Huambo‐Cabanaconde fault system, marked by intense seismicity over an area of about 50 × 30 km2 ${\mathrm{k}\mathrm{m}}^{2}$.
Jose‐Luis Torres +11 more
wiley +1 more source
Material-Sensitive and Thickness-Resolved Transmission Imaging Using Coherent Extreme Ultraviolet Radiation. [PDF]
Zhang F +5 more
europepmc +1 more source
Abstract The integration of satellite‐based observations into hydrological models offers transformation potential for improving discharge predictions globally, especially in regions lacking in situ measurements. This study presents CTRIP‐HyDAS, a global‐scale hydrological data assimilation framework that merges SWOT‐derived discharge observations with ...
Kaushlendra Verma +3 more
wiley +1 more source

