Results 181 to 190 of about 928,593 (318)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Life lost due to the COVID-19 pandemic: A model-based cohort analysis of mortality displacement in the registered population of England. [PDF]

PLoS One
Hughes A, Barnard S, Bauer-Staeb C, Holleyman R, Dunn S, Fryers P, Newton JN, Fitzpatrick J, Burton P, Goldblatt P.   +9 more
europepmc   +1 more source

Education for IDPs: poor marks [PDF]

Forced Migration Review, 2005
Brookings Bern Project on Internal Displacement
doaj  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Mechanical Property Evolution and Load Monitoring Method of Laminated Elastomeric Bridge Bearings Under Temperature Effects. [PDF]

Sensors (Basel)
He M, Liu X, Deng N.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Internal Displacement in the Context of Disasters and Adverse Effects of Climate Change: Submission to the High-Level Panel on Internal Displacement by the Envoy of the Chair of the Platform on Disaster Displacement

, 2020
Entwisle Chapuisat, Hannah, Kälin, Walter   +1 more
core  

A dual-interface load transfer model for precast concrete-cored cemented soil piles considering progressive damage. [PDF]

PLoS One
Liang H, Zhu Y, Xu L, Wu H, Zhang J, Xu B, Cao K.   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A solution algorithm for calculating the preload of T-type clamp bolts based on multiphysics coupling. [PDF]

PLoS One
Yang Y, Ou Y, Lin R, Ding Z, Zhang H, Liu Y.   +5 more
europepmc   +1 more source