Results 41 to 50 of about 2,189,086 (300)

Resonant speed meter for gravitational wave detection [PDF]

open access: yes, 2008
Gravitational-wave detectors have been well developed and operated with high sensitivity. However, they still suffer from mirror displacement noise. In this paper, we propose a resonant speed meter, as a displacement noise-canceled configuration based on
Atsushi Nishizawa   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Heterogeneous effects of climate change on displacement-inducing disasters

open access: yesFrontiers in Climate
With an estimated 357.7 million internal displacements caused since 2008, weather-related disasters are a major driver of human mobility worldwide. As climate change is projected to increase the frequency and intensity of extreme weather events in many ...
Robert Beyer   +4 more
doaj   +1 more source

Journey Through the Groan Zone with Academics and Practitioners: Bridging Conflict and Difference to Strengthen Disaster Risk Reduction and Recovery Work

open access: yesInternational Journal of Disaster Risk Science, 2018
Academic-practitioner divides in disaster management and research can be persistent and pernicious, bearing consequences for disaster survivors and future affected populations.
Katherine E. Browne   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Modelling displacement

open access: yesForced Migration Review, 2015
Although those seeking a single global prediction will be disappointed, today’s models of climate change- and disaster-induced displacement can provide a range of scenarios for specific countries, regions or hotspots.
Justin Ginnetti
doaj  

Migration corridors in Africa and access to health services: Current challenges and a path forward for research and practice

open access: yesJournal of Public Health in Africa
This commentary discusses migration corridors on the African continent and access to health services. It stems from a workshop on migration corridors held in South Africa and reflects the interdisciplinary collaborative dialogue on migration journeys and
Edward Kirumira   +3 more
doaj   +1 more source

Frequency-tunable metamaterials using broadside-coupled split ring resonators [PDF]

open access: yes, 2010
We present frequency tunable metamaterial designs at terahertz (THz) frequencies using broadside-coupled split ring resonator (BC-SRR) arrays. Frequency tuning, arising from changes in near field coupling, is obtained by in-plane horizontal or vertical ...
A. C. Strikwerda   +7 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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