Results 111 to 120 of about 2,383,636 (277)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

N>>2: Multi-speaker display systems for virtual reality and spatil audio projection

, 1998
Presented at 5th International Conference on Auditory Display (ICAD), Glasgow, UK, November 1-4, 1998.Presented at 5th International Conference on Auditory Display (ICAD), Glasgow, UK, November 1-4, 1998.This paper describes multi-speaker display systems
Cook, Perry R, Tzanetakis, Georgos, Trueman, Dan, Essl, Georg   +3 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Investigation of system latency detection threshold of virtual auditory display

, 2006
Presented at the 12th International Conference on Auditory Display (ICAD), London, UK, June 20-23, 2006.Presented at the 12th International Conference on Auditory Display (ICAD), London, UK, June 20-23, 2006.It is important in a virtual auditory display (
Iwaya, Y., Suzuki, Y., Yairi, S.
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Doing Science on Auditory Display Design in the Cockpit: Merging Laboratory Rigor and the Aircraft Cockpit Environment

, 2007
Presented at the 13th International Conference on Auditory Display (ICAD2007) June 26-29, 2007 in Montréal, Canada.This paper will discuss a human-system and application centered approach to the conduct of research on auditory alerting system design ...
Simpson, Carol A
core   +1 more source

Electrohydrodynamic printing for high resolution patterning of flexible electronics toward industrial applications

InfoMat
Electrohydrodynamic (EHD) printing technique, which deposits micro/nanostructures through high electric force, has recently attracted significant research interest owing to their fascinating characteristics in high resolution (
Zhouping Yin, Dazhi Wang, Yunlong Guo, Zhiyuan Zhao, Liqiang Li, Wei Chen, Yongqing Duan   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source