Results 211 to 220 of about 403,329 (307)

Amygdala-putamen connectivity links gratitude to greater well-being. [PDF]

open access: yesDialogues Clin Neurosci
Liu G   +5 more
europepmc   +1 more source

Barriers and Enablers for Effective Support Coordination in the National Disability Insurance Scheme

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Support coordinators act as intermediaries between the National Disability Insurance Scheme (NDIS) and participants, facilitating access to funded supports. To optimise outcomes, they must navigate NDIS complexities, identify services that meet individual needs and engage with diverse stakeholders.
Sharyn McDonald   +3 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Temperature‐Controlled Radiofrequency for Severe Nasal Airway Obstruction: A Non‐Inferiority Comparison With Surgical Intervention

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Temperature‐controlled radiofrequency (TCRF), septoplasty (ST) with turbinate reduction, and functional rhinoplasty (FR) are treatment options for nasal airway obstruction (NAO) and nasal valve dysfunction (NVD), but no direct comparison of these procedures has been performed. Methods This prospective, open‐label, non‐inferiority (
Greg Davis   +13 more
wiley   +1 more source

Research progress on biomarkers of traumatic brain injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen   +8 more
wiley   +1 more source

Photoactivated Signaling Networks using DNA‐Based Synthetic Organelles as Biomimetic Protocells

open access: yesAngewandte Chemie, EarlyView.
Light‐triggered intercommunication between two types of organelle‐loaded liposomes lead to DNAzyme‐mediated on transcription‐guided structural reconfiguration of the organelles. ABSTRACT Membraneless organelles formed by phase‐separated nucleic acid or protein condensates play vital roles in regulating cellular functions.
Huiying Xue   +6 more
wiley   +2 more sources

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

open access: yesAdvanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr   +9 more
wiley   +1 more source

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