Results 181 to 190 of about 13,427 (290)

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Cardiovascular Safety Signals of Osteoporosis Therapies: A FAERS Pharmacovigilance Study. [PDF]

Mediterr J Rheumatol
Sondhi M, Singh N, Carkin J, Hughes G.
europepmc   +1 more source

Recovery of Four Commercial Fish Stocks in Lake IJsselmeer (The Netherlands) After Major Fishery Management Interventions

Fisheries Management and Ecology, EarlyView.
ABSTRACT Sustainable management of inland fisheries presents major challenges because it often involves complex and open access systems. Lake IJsselmeer is among the largest freshwater lakes in western Europe and supports active commercial fisheries.
Joey J. J. Volwater, Justin C. Tiano, Kelly Chin, Joep J. de Leeuw   +3 more
wiley   +1 more source

Posterior reversible encephalopathy syndrome across 22 VEGF-pathway inhibitors in the FDA adverse event reporting system: reporting patterns and reporting-interval characteristics. [PDF]

Front Pharmacol
Li J, Cheng Y, Yang Y.
europepmc   +1 more source

Histopathological stratification of primary aldosteronism using the CYP11B2 size ratio: first evaluation in clinical routine

Histopathology, EarlyView.
CYP11B2 immunohistochemistry identifies aldosterone‐producing nodules and enables objective subtyping using the B2 ratio (B2R), defined as the size ratio between the largest and second‐largest CYP11B2‐positive nodules. A B2R ≥8.1 indicates classical histology with a dominant lesion and high likelihood of cure, whereas B2R <8.1 reflects non‐classical ...
Adam Stenman, Tim Nilsson, Henrik Falhammar, C. Christofer Juhlin   +3 more
wiley   +1 more source

Autoimmune Reporting Signals in FAERS Reports Listing COVID-19 Vaccines as Suspect Products: An Active-Comparator Disproportionality Analysis. [PDF]

Int J Environ Res Public Health
Messova AM, Sanbayev M, Abdrahmanova ST, Temirkhanova R, Mussin NM, Tamadon A.   +5 more
europepmc   +1 more source

In Defence of Walkability as a Crime Prevention Strategy

The Howard Journal of Crime and Justice, EarlyView.
ABSTRACT New Urbanist ideas promoting walkability have many benefits. But they are criticised by proponents of crime prevention through environmental design (CPTED), who blame street connectivity for facilitating target recognition, providing access and escape routes and weakening informal surveillance.
Jose Pina‐Sánchez, Ian Loader
wiley   +1 more source

Systematic analysis of adverse reaction signals induced by leflunomide, upadacitinib, and baricitinib in the treatment of rheumatoid arthritis: a FAERS database analysis. [PDF]

Front Med (Lausanne)
Dang J, Shu L.
europepmc   +1 more source

Unconditional Variance Estimation Under Complex Surveys

International Statistical Review, EarlyView.
Summary The unconditional framework treats the samples and the variables of interest as random variables. This is particularly suitable with analytic inference, when modelling survey data. We show that variance estimation does not involve finite population corrections and joint‐inclusion probabilities, even with large sampling fractions and under ...
Yves G. Berger
wiley   +1 more source

Safety assessment for ibuprofen using disproportionality analysis: a decade of data from the Romanian national pharmacovigilance system. [PDF]

Front Pharmacol
Buciuman CA, Butuca A, Frum A, Gligor FG, Ganea M, Vicaş LG, Marian E, Gligor O, Dobrea CM, Moisa CF, Pallag A, Jurca T, Morgovan C.   +12 more
europepmc   +1 more source