Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
200 years of KIT/TH Karlsruhe, 125 Years of Polymer Science in Karlsruhe: The Place Where Staudinger's Polymer Research Started. [PDF]
Macromol Rapid CommunWilhelm M.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Retraction notice to "Optimal rainwater harvesting locations for arid and semi-arid regions by using MCDM-based GIS techniques" [Heliyon 11 (2025) e42090]. [PDF]
HeliyonHassan WH, Mahdi K, Kadhim ZK.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Retraction notice to "Exploring the application of ICTs in decarbonizing the agriculture supply chain: A literature review and research agenda" [Heliyon 10 (2024) e29564]. [PDF]
HeliyonEl Jaouhari A +4 more
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Retraction notice to "Decision algorithm for educational institute selection with spherical fuzzy heronian mean operators and Aczel-Alsina triangular norm" [Heliyon 10 (2024) e28383]. [PDF]
HeliyonHussain A +5 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Retraction notice to "Electrifying energy storage by investigating the electrochemical behavior of CoCr<sub>2</sub>O<sub>4</sub>/graphene-oxide nanocomposite as supercapacitor high performance electrode material" [Heliyon 10 (2024) e40702]. [PDF]
HeliyonShafique R +6 more
europepmc +1 more source