Results 121 to 130 of about 170,789 (315)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
WTO Dispute Settlement: General Appreciation and the Role of India
On 1 January 1995, the Understanding on Rules and Procedures Governing the Settlement of Disputes (DSU) entered into force. Until August 2006, the DSU has since been applied to 348 complaints – more cases than dispute settlement under the GATT 1947 had ...
Zimmermann, Thomas A.
core
, 2009 This paper, while broadly located within reforming the labour market policy debate, is specifically focused on one aspect of the labour regulatory regime, namely the dispute resolution system.
Pauw, Kalie +2 more
core
Essential Dispute Resolution for SQE1
, 2023 Essential Dispute Resolution for SQE1 explains the key principles of dispute resolution in a clear, easy-tofollow style. Principles are introduced and illustrated with reference to realistic factual examples, commonly used court forms, and factual ...
Waters, B.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Resolution (Columbus, Ohio : Online)
, 2004 Semiannual; No. 04-1 (2004)-; Title from caption (viewed Feb.
Ohio Commission on Dispute Resolution and Conflict Management.
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Evolution and Utilization of the GATT/WTO Dispute Settlement Mechanism
This paper provides a theoretical framework of dispute settlement to explain the surge in blocking incidence of GATT panel reports during the 1980s and the variations in withdrawn incidence versus total disputes across different decades of the GATT ...
Pao-li Chang
core
Children’s Dispute Resolution in Hong Kong: The Need for Reform
, 2010 This article considers the need for the establishment in Hong Kong of (i) specialised children’s dispute resolution procedures that are less adversarial, more child-focused and allow for greater direct participation by children and young people, and (ii)
Lynch, KL, Wong, M
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source