Results 211 to 220 of about 654,032 (293)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Mapping Care Practices and Service Delivery Models for Refugee and Displaced Families in Private Hosting Arrangements: A Scoping Review. [PDF]

Nurs Rep
Al-Hamad A, Yasin YM, Yasin L, Zhang A.
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

An innovative blockchain framework for strengthening security and efficiency in banking. [PDF]

Sci Rep
Ahammad MS, Maliha M, Nila NE, Islam MS.
europepmc   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Public policies addressing unhealthy diets in the South-East Asia region: identifying and countering the arguments that undermine policy implementation. [PDF]

Health Policy Plan
Wood B, Sievert K, Sharma N, de Silva PA, Sacks G, Gupta R, Mialon M, Shabnam F, Reeve E.   +8 more
europepmc   +1 more source

Investment Court System or ‘Regional’ Dispute Settlement?: The Uncertain Future of Investor-state Dispute Settlement [PDF]

Bond Law Review
Umair Ghori
doaj  

Governance of prepaid consumption in China's sports industry based on collaborative governance theory: theoretical framework, realistic dilemmas, and practical pathways. [PDF]

Front Sports Act Living
Su J, He J.
europepmc   +1 more source

How to advance employment discrimination research in an era of big data and analytics. [PDF]

Front Sociol
Lopez YP, LaVan H, Martin WM.
europepmc   +1 more source

Trends in Pediatric Malpractice Claims at a Tertiary Children's Hospital. [PDF]

Healthcare (Basel)
Defraia B, Faccioli S, Gori E, Gualco B, Grifoni R, Pacitti M, Pierro F, Lombardi I, Pinchi V, Focardi M.   +9 more
europepmc   +1 more source