Results 41 to 50 of about 509,052 (284)

Ugoda – lepszy sposób rozwiązania sporu?

open access: yesActa Iuris Stetinensis, 2017
The very wide range of legal relationships which makes a possibility to conclude a settlement shows its great importance in practice. Similarly, it is necessary to assess the need for its dissemination, not only in court proceedings, because the amicable
Aneta Biały
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Rekonstruksi Kewenangan Penyelesaian Perselisihan Hasil Pemilihan Umum

open access: yesJurnal Konstitusi, 2016
Construction of authority in the settlement of dispute over the result of local election is still in transformation to become the ideal format. At the same time, the authority in the settlement of election dispute which is distributed to many agencies ...
Refly Harun
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Mapping the Mechanism for Trade Dispute Resolution in the Bilateral Free Trade Agreement Between Indonesia and Partner Countries

open access: yesJurnal Hukum Internasional
Indonesia actively promotes international trade liberalization through various free trade agreements (FTAs) with partner nations. This study focuses on the dispute settlement mechanisms (DSM) within Indonesia’s bilateral FTAs, given that most partners ...
Garuda Wiko, Fatma Muthia Kinanti
doaj   +1 more source

The deficiency of dispute settlement mechanism seen in Chinese construction field from FIDIC

open access: yesMATEC Web of Conferences, 2018
Since formally introduced the friendly Amicable Settlement mechanism in 1987, FIDIC’ s efforts to promote and improve the alternative dispute settlement mechanism for construction work have been greatly developed.
Li Dezhi, Zhang Huiyan, Fang Xuehua
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Investor-State Dispute Settlement Mechanism: The Quest for a Workable Roadmap

open access: yesUtrecht Journal of International and European Law, 2013
The last decade has witnessed an unprecedented increase in the use of investor-State arbitration, highlighting numerous shortcomings of the existing investor-State dispute settlement system.
Sachet Singh, Sooraj Sharma
doaj   +3 more sources

Asian Values in International Dispute Settlement: Issues of Parallel Jurisdiction

open access: yesJurnal Hukum Internasional
Asian Values promoted significant economic growth to Asian societies in 1990s but were challenged by the 1997-1998 financial crisis. Engaging in regional trade agreements (RTAs) can enhance market access and keep regulatory cooperation, the number of ...
HaiJing Huang, Tze Chin Ong
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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