Results 81 to 90 of about 549,980 (345)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Kant\u27s Political Theory and Philosophy of History [PDF]

open access: yes
Kant combined two traditional approaches in his political theory, reference to a utopian and ideal universal moral order in common with Plato, Thomas More, and Jean Jacques Rousseau and an analysis of the pursuit of individual self-interest leading to ...
Kain, Philip J.
core  

Application of Environmental Conflict Resolution to Public Interest Issues in Water Disputes [PDF]

open access: yes
This article examines the role of environmental conflict resolution (ECR) in the public interest issues of water disputes. The article endeavours to  illustrate the strengths and weaknesses of a range of alternative dispute resolution (ADR) and ...
Craig, Donna, Jeffrey QC, Michael
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Role of Lawyers in Family Law Disputes

open access: yesZbornik Pravnog Fakulteta u Zagrebu, 2018
Since lawyers in most cases are the first to come into contact with families where there is a conflict, it is important to re-examine their role and ability to guide the parties to a different and a more appropriate way of resolving the dispute.
Anica Čulo Margaletić
doaj  

THE INTEREST OF CHILDREN IN PARENTAL DISPUTES

open access: yesTHE LAW AND THE BUSINESS IN THE CONTEMPORARY SOCIETY
Parental disputes regarding all issues related to their children have, over the past decade, turned into in-depth court battles and extrajudicial wars. In this case, instead of the interest of their children being the leading one, unacceptable, extreme and even bordering on absurd actions and in actions are reached, which not only create prerequisites ...
openaire   +1 more source

Revitalizing Multilateral Governance at the World Trade Organization Policy Brief based on the Report of the High-Level Board of Experts on the Future of Global Trade Governance. Bertelsmann Policy Brief 2018 [PDF]

open access: yes
If international trade is not governed by rules, mere might dictates what is right. The World Trade Organization (WTO) serves as a place where trade policy issues are addressed, disputes arbitrated, legal frameworks derived and enforced.
De Geus, Aart, Esche, Andreas
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The WTO Dispute Settlement System 1995-2010: Some Descriptive Statistics [PDF]

open access: yes
The Dispute Settlement (DS) system is a central feature of the World Trade Organization (WTO) Agreement. This compulsory and binding two-level mechanism for the adjudication of disputes between WTO Members is the most active among international courts ...
Horn, Henrik   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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