Results 111 to 120 of about 555,218 (350)

Standard arbitration agreements: a viable means for antitrust damages claims?

open access: yesMarket and Competition Law Review
Following the judgment of the Court of Justice and especially the Opinion of the Advocate General in the CDC Hydrogen Peroxide case, arbitration agreements on disputes concerning damages for infringements of the competition rules of the TFEU have been ...
Antonio Robles Martín-Laborda
doaj   +1 more source

Sukcesja pojugosłowiańska – kwestie granic

open access: yesPoliteja, 2019
Slavonic Succession – Border Issues The main research goal of the article was to determine whether there are disputes between the Yugoslavian countries over the borders that divide them, and which of them are active disputes, and which of them have ...
Ewa Bujwid-Kurek
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

THE NEW LAW ON ADMINISTRATIVE DISPUTES

open access: yesIustinianus Primus Law Review, 2020
This paper explores the main features of the new Law on Administrative Disputes, which shall come into force in May 2020, so as to ensure effective judicial protection of citizens and legal entities in administrative disputes.
Edita Naskovska
doaj  

Defending and Disputing Human Rights

open access: yesDe Ethica
This article demonstrates how ethics, understood as the theoretical analysis of morality, contribute to the discussion of disagreements over human rights. It starts with an elaboration on the disagreements between proponents of human rights and proceeds to disagreements between human rights proponents and sceptics.
openaire   +2 more sources

Self-Determination in International Mediation: Some Preliminary Reflections [PDF]

open access: yes
Few concepts have generated as much discussion in the post-war international legal system as that of “self-determination.” Scholars debate the proper identity of the selves endowed with this right, its boundaries, and its normative relevance.
Nolan-Haley, Jacqueline
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Sensible Agnosticism: An Updated Approach to Domain-Name Trademark Infringement [PDF]

open access: yes
The Internet era has brought a new battlefield to U.S.-trademark-law disputes: domain names. Trademark owners have vigorously challenged the registration of domain names that consist of-or merely include-their trademarked terms, suing these domain-name ...
Reed, Shiveh Roxana
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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