Results 71 to 80 of about 9,180,255 (299)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Disruption Management for Commercial Aviation [PDF]

open access: yes, 2012
Airlines are constantly facing operational disruptions such as reduced airport capacity because of bad weather or strikes, unexpected aircraft unavailability due to mechanical failures, and delayed or cancelled flights.
682   +5 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The ITPA disruption database

open access: yes
A multi-device database of disruption characteristics has been developed under the auspices of the International Tokamak Physics Activity magneto-hydrodynamics topical group.
Riccardo, V.   +9 more
core   +1 more source

Academy of Management Proceedings

open access: yes, 2018
We develop a contingency view of the contribution of different types of dynamic capabilities to firm external fitness in context of market disruption.
Peeters, Carine
core   +1 more source

Resource Management of Disruption Tolerant Networks [PDF]

open access: yes, 2008
Disruption tolerant networks (DTNs) differ from traditional networks due to their special characteristics such as frequent partitions, intermittent connectivity, and message delivery delay. This paper presents a new idea for the resource management of sparse disruption tolerant networks where the density of nodes is insufficient to support direct end ...
Iyad Tumar, Jürgen Schönwälder
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Disruption management in single wagonload transport

open access: yesTransportation Research Interdisciplinary Perspectives
In highly utilised rail networks, disruptions can quickly have extensive impact on overall network performance, significantly affecting the reliability and efficiency of transport chains.
Maurice Krauth   +3 more
doaj   +1 more source

Production disruption management for R/M integrated supply chain using system dynamics methodology

open access: yesInternational Journal of Sustainable Engineering, 2017
The impacts of production disruption in Remanufacturing/Manufacturing (R/M) integrated supply chain on the sales and the methods of production disruption management were studied. A system dynamics model for the R/M integrated supply chain with production
Qiaolun Gu, Tiegang Gao
doaj   +1 more source

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