Results 171 to 180 of about 349,129 (300)

"Disruptive Behavior" or "Expected Benefit" Are Rationales of Seclusion Without Prior Aggression. [PDF]

Front Psychiatry, 2022
Vruwink FJ, VanDerNagel JEL, Noorthoorn EO, Nijman HLI, Mulder CL.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Emotion and Executive Dysfunction in Young Children with Disruptive Behavior Disorders: The Role of Cardiac Autonomic Balance. [PDF]

J Psychopathol Behav Assess
Graziano PA, Hernandez M, Steven Dick A.
europepmc   +1 more source

Treatment of childhood disruptive behavior disorders and callous-unemotional traits: a systematic review and two multilevel meta-analyses. [PDF]

J Child Psychol Psychiatry, 2023
Perlstein S, Fair M, Hong E, Waller R.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Disentangling the neural underpinnings of response inhibition in disruptive behavior and co-occurring ADHD. [PDF]

Eur Child Adolesc Psychiatry
Saraçaydın G, van Rooij D, Kleine-Deters R, Messchendorp M, Naaijen J, Penzol MJ, Rosa M, Aggensteiner PM, Baumeister S, Holz N, Banaschewski T, Saam M, Schulze UME, Sethi A, Craig M, Castro-Fornieles J, Arango C, Walitza S, Werhahn J, Brandeis D, Franke B, Ruisch IH, Buitelaar JK, Dietrich A, Hoekstra PJ.   +24 more
europepmc   +1 more source

Contemporary screen time modalities and disruptive behavior disorders in children: a prospective cohort study. [PDF]

J Child Psychol Psychiatry, 2023
Nagata JM, Chu J, Ganson KT, Murray SB, Iyer P, Gabriel KP, Garber AK, Bibbins-Domingo K, Baker FC.   +8 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Relationship Between Personality Inventory for DSM (PID-5) Domains and Disruptive Behavior Disorders. [PDF]

Scand J Child Adolesc Psychiatr Psychol
Akça ÖF, Cano K, Sharp C.
europepmc   +1 more source