Results 171 to 180 of about 351,595 (299)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The influence of learning interest on complex mathematical problem-solving ability: the mediating effect of classroom disruptive behavior and self-efficacy. [PDF]

Front Psychol
Wang Y, Xie B, Zhou L, Wang L, Jin H.
europepmc   +1 more source

"Disruptive Behavior" or "Expected Benefit" Are Rationales of Seclusion Without Prior Aggression. [PDF]

Front Psychiatry, 2022
Vruwink FJ, VanDerNagel JEL, Noorthoorn EO, Nijman HLI, Mulder CL.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Parent-Child Interaction Therapy for Disruptive Behavior: A Systematic Review of Effectiveness in Different Settings. [PDF]

J Clin Med
Calderone A, Piccolo A, Latella D, De Luca R, Corallo F, Quartarone A, Militi A, Cucinotta F, Calabrò RS.   +8 more
europepmc   +1 more source

Antipsychotics in the Management of Disruptive Behavior Disorders in Children and Adolescents: An Update and Critical Review. [PDF]

Biomedicines, 2022
Rajkumar RP.
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Emotion and Executive Dysfunction in Young Children with Disruptive Behavior Disorders: The Role of Cardiac Autonomic Balance. [PDF]

J Psychopathol Behav Assess
Graziano PA, Hernandez M, Steven Dick A.
europepmc   +1 more source

Treatment of childhood disruptive behavior disorders and callous-unemotional traits: a systematic review and two multilevel meta-analyses. [PDF]

J Child Psychol Psychiatry, 2023
Perlstein S, Fair M, Hong E, Waller R.
europepmc   +1 more source