Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke +5 more
wiley +1 more source
The success of entrepreneurship based on the theory of disruptive innovation: Marketing perspective
Cogent Business & ManagementThis study explores the intersection of disruptive innovation principles and marketing strategies in fostering entrepreneurial success within the Arab region, a culturally and economically diverse context characterized by rapid digital transformation ...
Shereen Aly Hussien Aly Abdou
doaj +1 more source
COVID-19's Disruptive Innovation: Accelerating the Academic Preparation of Professional Nurses' Ambulatory and Telehealth Roles. [PDF]
Nurse Lead, 2022 Kollman S, Braegger D, Head B.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Beyond Status Quo: Why is Transdisciplinary Communication Instrumental in Innovation? [PDF]
Journal of Systemics, Cybernetics and InformaticsIn an era of rapid technological advancements and complex societal challenges, the imperative for disruptive innovation has never been more acute. The International Multi-Conference on Complexity, Informatics, and Cybernetics (IMCIC) 2024 served as a ...
James Lipuma, Cristo Leon
doaj
Harnessing Disruptive Innovation: A Conceptual Model for SME Growth and Adaptation
BusinessesIn the context of sustaining innovation, small and medium enterprises (SMEs) strive to enhance their market position through product improvements. However, globalization and rapid technological advancements pose significant challenges, urging SMEs to ...
Hanlie Smuts +6 more
doaj +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
The Role and Meaning of the Digital Transformation As a Disruptive Innovation on Small and Medium Manufacturing Enterprises. [PDF]
Front Psychol, 2021 Roblek V, Meško M, Pušavec F, Likar B.
europepmc +1 more source
Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial
Arthritis Care &Research, EarlyView.Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham +29 more
wiley +1 more source