Results 71 to 80 of about 1,729,437 (252)
Retrospective analysis of patients with probable DSM-5 disruptive mood dysregulation disorder
Psychiatry and Clinical Psychopharmacology, 2021 This study has not been submitted before and is not under consideration at another journal. All of the authors have contributed to the study and approve of its contents. The authors have no conflicts of interest to disclose.
Zehra Zehra Topal +4 more
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Psychiatric Comorbidities in Children With ASD: Autism Centre Experience
Frontiers in Psychiatry, 2021 Autism spectrum disorder (ASD) is a neurodevelopmental disorder with social communication deficits, restricted interests, and repetitive behaviours. In this lifelong condition the core features that cause impairment may also be expanded by behavioural ...
Iva Ivanović
doaj +1 more source
Emotion Regulation in Severe Irritability and Disruptive Mood Dysregulation Disorder
, 2017 Chapter 14 discusses emotion dysregulation in pediatric irritability and disruptive mood dysregulation disorder (DMDD). Irritability refers to a low threshold for experiencing negative affect, namely frustration and anger in the context of blocked goal ...
Ellen Leibenluft +2 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source
Advanced Science, EarlyView.This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle
Advanced Science, EarlyView.This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin +9 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
Switch phenomenon in bipolar disorders: What is it?
Telangana Journal of Psychiatry, 2016 The phenomenon of Affective switch process is not well understood. It is difficult to differentiate switch from natural course of emergence of Manic/Hypomanic episodes.
Anand Bhogaraju
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تحقیقات نظام سلامت, 2020 Background: One of the essential factors in regulating the excitement of irritable children is mothers’ parenting style which is effective in self-controlling of these children; therefore, the purpose of this study is to develop a parental model based on
Azam Shahmohammadi-Ghahsareh +3 more
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