Results 111 to 120 of about 479,019 (353)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

“BODY-SNATCHING”: Changes to coroners legislation and possible Māori responses [PDF]

, 2009
The term body-snatcher has enjoyed a renaissance in the media recently, as various Māori have moved to reclaim their deceased relations. From a Māori perspective, the claiming of bodies has nothing to do with body-snatching, a term that referred to ...
Mika, Carl Te Hira
core   +1 more source

Dermatological Malignancies at a University Teaching Hospital in north-western Tanzania: A Retrospective Review of 154 Cases [PDF]

, 2012
Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution ...
Chalya, Phillipo L., Gilyoma, Japhet M., Kahima, Kahima J., Kanumba, Emmanuel S., Masalu, Nestory, Mawala, Brian, Rambau, Peter   +6 more
core   +2 more sources

Smart Learning: An Interactive Dissection Simulator for Medical Students Through Virtual Reality [PDF]

, 2023
Sheikh Asad Jamal, Alyan Khan, Samiullah Shah, Shayan Waris Siddiqui, Sallar Khan   +4 more
openalex   +1 more source

DISSECTING THE NEED FOR DISSECTION IN VETERINARY IN MEDICAL TRAINING

Slovenian Veterinary Research
As veterinary and human medicine education evolves, instructors can now incorporate a range of innovative anatomy tools, from low-fidelity models to high-fidelity simulators, 3D printing, dissection software, and augmented/virtual reality. However, cadaveric dissection in line with ethical animal use, guided by the 4Rs: replacement, reduction ...
Valentina Kubale Dvojmoč, William Perez, Catrin S. Rutland   +2 more
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Integrated virtual and cadaveric dissection laboratories enhance first year medical students’ anatomy experience: a pilot study

BMC Medical Education, 2019
Background Radiology integration into medical anatomy courses is well established, but there is a paucity of literature on integrating virtual dissection into cadaveric dissection laboratories.
Kathryn E. Darras, Rebecca Spouge, Rose Hatala, Savvas Nicolaou, Jeff Hu, Anne Worthington, Claudia Krebs, Bruce B. Forster   +7 more
doaj   +1 more source

Sleep apnea and the impact on cardiovascular risk in patients with Marfan syndrome [PDF]

, 2019
Background: Marfan syndrome (MFS) is an inherited connective tissue disorder characterized by ectopia lentis, aortic root dilation and dissection and specific skeletal features.
Bauters, Fré, De Backer, Julie, De Groote, Katya, De Wilde, Hans, De Wolf, Daniël, Dhondt, Karlien, Hertegonne, Katrien, Jordaens, Luc, Muiño Mosquera, Laura   +8 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Coronal Plane: Cristin Millett

, 2018
Coronal Plane is the culmination of Millett’s research on the anatomical theater at the University of Padua built in 1594, the oldest surviving anatomy theater in the world.
Egan, Shannon, Linden, Grace
core