Results 51 to 60 of about 476,666 (340)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

An unusual occurrence of a four-headed psoas major: a case report

Folia Morphologica
BACKGROUND: While many structures within the human body demonstrate anatomical variations, this is not typically the case for the iliopsoas muscle complex.
Marta Pośnik, Nicol Zielinska, Konrad Kurtys, Krzysztof Koptas, Łukasz Olewnik   +4 more
doaj   +1 more source

Chronic β-blocker therapy improves outcome and reduces treatment costs in chronic type B aortic dissection [PDF]

, 2017
Objectives: To compare the medical treatment of chronic type B aortic dissection with β-blockers versus other antihypertensive treatments in terms of their requirement for surgical intervention and treatment costs.
Genoni, Michele, Graves, Kirk, Jenni, Rolf, Paul, Matthias, Seifert, Burkhardt, Turina, Marko   +5 more
core  

Atenolol versus losartan in children and young adults with Marfan's syndrome [PDF]

, 2014
BACKGROUND : Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers.
Atz, A.M., Backer, J. de, Benson, D.W., Bradley, T.J., Braverman, A.C., Chen, S., Colan, S.D., Dietz, H.C., et al., Gelb, B.D., Grossfeld, P.D., Klein, G.L., Lacro, R.V., Lai, W.W., Levine, J.C., Liou, A., Loeys, B.L., Mahony, L., Markham, L.W., Olson, A.K., Paridon, S.M., Pearson, G.D., Pemberton, V.L., Pierpont, M.E., Pyeritz, R.E., Radojewski, E., Roman, M.J., Sharkey, A.M., Sleeper, L.A., Stylianou, M.P., Tierney, E.S., Wechsler, S.B., Yetman, A.T., Young, L.T.   +33 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Role of Traditional Dissection in Medical Education

Education in Medicine Journal, 2010
Dissection is being sidelined in medical education .Computers and other alternative teaching tools are replacing cadavers in the modern anatomy curriculum. Evidence based literature suggests that cadaver dissection is highly effective in establishing and retaining anatomy concepts.
Tabinda Hassan, Hussein Ageely, Dieba Hasan   +2 more
openaire   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]

, 2018
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin, Alecu, Lucian, Cristian, Balalau, Hainarosie, Razvan, Jecan, Radu, Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Poiana, Catalina, Slavu, Iulian, Tomescu, Luminita, Tulin, Raluca   +12 more
core   +1 more source

Early Complications After Radical Operations in Breast Cancer Patients [PDF]

, 2020
Breast cancer is one of the most common Malignancies in women. In many cases, a major component of complex treatment for breast cancer is surgery - radical mastectomy or radical breast resection.The aim of the work – to investigate the frequency and ...
Baranova, A. (Anna), Vinnyk, Y. (Yuri), Vlasenko, V. (Vadym)   +2 more
core  

Mathematical modeling of thrombus formation in idealized models of aortic dissection: Initial findings and potential applications [PDF]

, 2016
Aortic dissection is a major aortic catastrophe with a high morbidity and mortality risk caused by the formation of a tear in the aortic wall. The development of a second blood filled region defined as the “false lumen” causes highly disturbed flow ...
Menichini, C, Xu, XY
core   +1 more source