Results 51 to 60 of about 288,431 (247)

A very rare case of the accessory palmaris longus muscle and clinical significance

open access: yesFolia Morphologica
The palmaris longus muscle is located in the forearm region. Its morphological variability was noted during standard anatomical dissection of the upper limb. The muscle was characterised by a normal course, i.e.
Nicol Zielinska   +5 more
doaj   +1 more source

Assessment of the determinants of Knowledge, Attitude and Practice (KAP) of Ethiopian Medical Students towards ethical Cadaver Dissection

open access: yesTranslational Research in Anatomy, 2020
Introduction: Anatomy is one of the essential basic medical sciences and a key to understand the practice of medicine. Its stduy has been conventionally based around the use of cadaver dissection.
Madebo Ergano   +9 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Co-occurrence of a previously unreported double-headed accessory psoas major with an unusually positioned accessory iliacus muscle: case report

open access: yesFolia Morphologica
The iliopsoas muscle complex traditionally consists of the iliacus muscle and psoas major, occasionally including the psoas minor. These elements were distinguished based on their shared function and common distal attachment.
Marta Pośnik   +4 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Morphological variability of the piriformis muscle

open access: yesFolia Morphologica
BACKGROUND: The aim of the study is to create several classifications of the piriformis muscle (PM): proximal and distal attachments, potential fusions, and the relationship with the sciatic nerve.
Łukasz Olewnik   +8 more
doaj   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Teaching professionalism in cadaver dissection: medical students' perspective. [PDF]

open access: yesJ Med Ethics Hist Med, 2021
Khabaz Mafinejad M   +7 more
europepmc   +1 more source

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