Results 61 to 70 of about 278,974 (289)
Predictors of Manual Dexterity in Simulation-Based Cataract Surgery
Journal of Academic Ophthalmology, 2020 Introduction The aim of this study is to determine if prior experience with fine motor hobbies influences a surgeon-in-training's performance on a cataract surgical simulator.
Laura Palazzolo +3 more
doaj +1 more source
Spontaneous dissection of celiac trunk with concurrent splenic artery dissection [PDF]
Clinical and Experimental Emergency Medicine, 2015 Isolated spontaneous dissection of the celiac trunk is rarely diagnosed in acute abdominal pain. We present two cases of celiac trunk and splenic artery dissection with splenic infarction.
Seo In Lee +3 more
doaj +1 more source
Difficulty of Dissection: Which Anatomical Regions Are Hardest For Medical Students To Dissect?
The FASEB Journal, 2018 Cadaveric dissection in gross anatomy courses has long been considered the gold‐standard for instruction, but the difficulty associated with some dissections may lead to negative learning outcomes for those students adversely impacted by dissection experiences.
Sutton Williams +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Recent advances and changing face of anatomy teaching and learning in medical education
National Journal of Clinical Anatomy, 2019 Background A sound knowledge of human anatomy is a maj’or requirement for being a good physician or a practicing surgeon. Despite digitalization and modernization of education sector, traditional cadaveric dissection still occupies the leadership of ...
Mathew Joseph, Brijendra Singh
doaj +1 more source
The Lancaster Medical Book Club and the Dissection of Murderers
Morecambe Bay Medical Journal, 2023 Rhodes, Bryan +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source