Results 71 to 80 of about 459,893 (335)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A very rare case report: accessory head of the sartorius muscle

Folia Morphologica
The sartorius muscle belongs to the anterior compartment of the thigh. Morphological variations of this muscle are very rare, few cases being described in the literature.
Nicol Zielinska, Richard Shane Tubbs, Adrian Balcerzak, Łukasz Olewnik   +3 more
doaj   +1 more source

Blunt traumatic celiac artery avulsion managed with celiac artery ligation and open aorto-celiac bypass. [PDF]

, 2017
Traumatic celiac artery injuries are rare and highly lethal with reported mortality rates of 38-62%. The vast majority are caused by penetrating trauma with only 11 reported cases due to blunt trauma (Graham et al., 1978; Asensio et al., 2000, 2002 ...
Doben, Andrew R, Gross, Ronald I, Kravetz, Amanda, Kronick, Matthew D, Morris, Marvin E, Nahmias, Jeffry T   +5 more
core   +2 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Two variant muscles in the gluteal region

Folia Morphologica
The short lateral rotators of the thigh found in the gluteal region can have morphological variations. During anatomical dissection of a right lower limb, two variant structures were found in this region.
Nicol Zielinska, Richard Shane Tubbs, Piotr Łabętowicz, Łukasz Olewnik   +3 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Accessory slip of fibularis tertius to extensor digitorum longus — an unreported variant

Folia Morphologica
The fibularis tertius (FT) is one of three muscles which constitute the anterior compartment of the leg. The anatomical variants of this muscle usually pertain to its origins, number of final tendons or points, and shapes of insertions. In the particular
Andrzej Węgiel, Nicol Zielinska, Krystian Maślanka, Bartosz Gonera, Konrad Kurtys, Łukasz Olewnik   +5 more
doaj   +1 more source

Andreas Vesalius: Celebrating 500 years of dissecting nature [PDF]

, 2015
December 31st, 2014 marked the 500-year anniversary of the birth of Andreas Vesalius. Vesalius, considered as the founder of modern anatomy, had profoundly changed not only human anatomy, but also the intellectual structure of medicine. The impact of his
Elmaghawry, Mohamed, Thiene, Gaetano, Zampieri, Fabio, Zanatta, Alberto   +3 more
core   +1 more source

Difficulty of Dissection: Which Anatomical Regions Are Hardest For Medical Students To Dissect?

The FASEB Journal, 2018
Cadaveric dissection in gross anatomy courses has long been considered the gold‐standard for instruction, but the difficulty associated with some dissections may lead to negative learning outcomes for those students adversely impacted by dissection experiences.
Sutton Williams, Kenneth D. Thompson, Andrew Notebaert, Allan R. Sinning   +3 more
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source