Results 81 to 90 of about 459,893 (335)

Atenolol versus losartan in children and young adults with Marfan's syndrome [PDF]

, 2014
BACKGROUND : Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers.
Atz, A.M., Backer, J. de, Benson, D.W., Bradley, T.J., Braverman, A.C., Chen, S., Colan, S.D., Dietz, H.C., et al., Gelb, B.D., Grossfeld, P.D., Klein, G.L., Lacro, R.V., Lai, W.W., Levine, J.C., Liou, A., Loeys, B.L., Mahony, L., Markham, L.W., Olson, A.K., Paridon, S.M., Pearson, G.D., Pemberton, V.L., Pierpont, M.E., Pyeritz, R.E., Radojewski, E., Roman, M.J., Sharkey, A.M., Sleeper, L.A., Stylianou, M.P., Tierney, E.S., Wechsler, S.B., Yetman, A.T., Young, L.T.   +33 more
core   +2 more sources

The Lancaster Medical Book Club and the Dissection of Murderers

Morecambe Bay Medical Journal, 2023
     
Rhodes, Bryan, Fitzpatrick, Gill, Taylor, Adam, Wessels, Quenton   +3 more
openaire   +2 more sources

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Morphological variability of the leg muscles: potential pitfalls on ultrasound that await clinicians

Folia Morphologica
BACKGROUND: Although muscles and their tendons are not considered the most morphologically variable structures, they still manifest a substantial diversity of variants.
Marta Pośnik, Nicol Zielinska, Richard Shane Tubbs, Kacper Ruzik, Łukasz Olewnik   +4 more
doaj   +1 more source

Safety and efficacy of endoscopic submucosal dissection for rectal neoplasia: a multicenter North American experience. [PDF]

, 2019
Background and aims  Rectal lesions traditionally represent the first lesions approached during endoscopic submucosal dissection (ESD) training in the West. We evaluated the safety and efficacy of rectal ESD in North America.
Aadam, Abdul Aziz, Aihara, Hiroyuki, Andrawes, Sherif, Benias, Petros, Chang, Kenneth, Diehl, David L, Draganov, Peter V, Hashimoto, Rintaro, Hwang, Joo Ha, Inamdar, Sumant, Khara, Harshit S, Khashab, Mouen A, Khoshknab, Milad Pourmousavi, Kim, Raymond E, Kumta, Nikhil A, Lan, Gloria, Maniere, Thibaut, Natov, Nikola S, Ngamruengphong, Saowanee, Nosler, Michael J, Othman, Mohamed O, Perbtani, Yaseen B, Ramay, Fariha, Samarasena, Jason, Sethi, Amrita, Siegel, Amanda, Tabash, Abdalaziz, Tharian, Benjamin, Tomizawa, Yutaka, Wang, Andrew Y, Yang, Dennis, Zou, Baiming   +31 more
core   +1 more source

The Hybrid Approach to Intervention of Chronic Total Occlusions [PDF]

, 2015
The "hybrid" approach to chronic total occlusion (CTO) percutaneous coronary intervention (PCI) was developed to provide guidance on optimal crossing strategy selection.
Banerjee, S, Brilakis, ES, Christopoulos, G, Kotsia, A, Rangan, BV, Rinfret, S, Spratt, J   +6 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

New perspectives - approaches to medical education at four new UK Medical Schools [PDF]

, 2004
To create more UK doctors, the government has funded an increase in medical student numbers of 57% (from 3749 to 5894)1 between 1998 and 2005. This has been done by increasing student places at existing medical schools; creating shortened programmes open
Campion, Peter, Howe, Amanda, Searle, Judy, Smith, Helen   +3 more
core   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A very rare case of the accessory palmaris longus muscle and clinical significance

Folia Morphologica
The palmaris longus muscle is located in the forearm region. Its morphological variability was noted during standard anatomical dissection of the upper limb. The muscle was characterised by a normal course, i.e.
Nicol Zielinska, Andrzej Borowski, Marek Drobniewski, Krystian Maślanka, Piotr Karauda, Łukasz Olewnik   +5 more
doaj   +1 more source