Results 211 to 220 of about 436,310 (315)

Necrotic ulcers in a HIV-positive man

JAAD Case Reports
Nina Lucia Tamashunas, MD, Sarah J. Williamson, MD, Evan Wypasek, DO, Katherine DiSano, MD, Stephen Somach, MD, Amy J. Ray, MD, David R. Crowe, MD   +6 more
doaj   +1 more source

Patient-Reported Health-Related Quality of Life Impact and Symptom Severity in Patients with Lyme Borreliosis in the Burden of Lyme Disease (BOLD) Study. [PDF]

Pathogens
Yu H, Mercadante AR, Halsby K, Loew-Baselli A, Tan Y, Edwards J, Angulo FJ, Begier E, Dzingina M, Berglund JS, Moniuszko-Malinowska A, Strle F, Stark JH, On Behalf Of The Bold Study Group.   +13 more
europepmc   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Fatal Catheter-Related Hematogenous Disseminated MSSA Sepsis in an Immunocompromised Lung Cancer Patient: A Case Report. [PDF]

Infect Drug Resist
Li Y, Zhao F.
europepmc   +1 more source

Disseminated Blastomycosis

The American Journal of Tropical Medicine and Hygiene
Hall, Ashton D., Patel, Kavya, Burch, Michael B., Rotert, Lea M.   +3 more
openaire   +2 more sources

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

<i>STAT1</i> gain-of-function variant in a previously healthy patient with disseminated <i>Mycobacterium genavense</i> infection. [PDF]

J Hum Immun
Thiagarajan K, Dong HV, Kuo CY, Thauland TJ, Pullarkat S, Butte MJ, Garcia-Lloret MI, Nielsen-Saines K.   +7 more
europepmc   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Catastrophic systemic reaction and fatal disseminated intravascular coagulation following high-pressure intrapelvic povidone-iodine instillation: A case report and review of possible mechanisms. [PDF]

Urol Case Rep
Quadir U, Para SA, Khawaja AR, Kannan G, Arsalan SS, Raina AB, Alam S, Nazir Y, Bhat OM, Wani AA, Ullah A.   +10 more
europepmc   +1 more source

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source