Results 241 to 250 of about 436,310 (315)

Disseminated Tuberculosis Mimicking Metastatic Cancer During Ruxolitinib Therapy for Polycythemia Vera: A Case Report and Literature Review. [PDF]

Am J Case Rep
Ono Y, Oka K, Ishikawa K, Shikata H, Kaneko M.   +4 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Survival Analysis in Cutaneous Leishmaniasis Patients: A Retrospective Cohort Study. [PDF]

Biomedicines
Leal JFC, Bezerra Silva CC, Nascimento MBS, Gonçalves RT, Fernandes LHG, Campos ASC, Araújo FM, Sampaio RNR, Barroso DH.   +8 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Disseminated cutaneous mast cell tumor in a South American coati (Nasua nasua). [PDF]

Vet Res Commun
Mazaro RD, Hartmann G, Cardoso D, Da Silva TC, Cogliati B, Kommers GD, Fighera RA.   +6 more
europepmc   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Disseminated intravascular coagulation as a prognostic factor in heatstroke: a retrospective cohort study based on Japanese insurance claims. [PDF]

Front Med (Lausanne)
Koami H, Furukawa Y, Ushijima H, Muroya D, Matsuoka T, Totoki T, Kandori K, Oishi T, Satoh K, Umemura Y, Yamakawa K, Hayakawa M, Okamoto K, Sakamoto Y.   +13 more
europepmc   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

Advanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song, Meng Wang, Xingyu Wu, Meng Cai, Bowen Li, Qi Wang, Xiaodong Guan, Qi Ding, Ruobing Wang, Hui Wang   +9 more
wiley   +1 more source

Probable Coxsackievirus Infection in an Immunocompetent Adult With Genital and Oral Ulcerations Mimicking Herpes Simplex Virus Infection and Behçet's Disease. [PDF]

Cureus
Gutierrez-Silva JC, Fontanet-Gomez N, Grand Barrios E, Aneja P, Chopra A.   +4 more
europepmc   +1 more source