Results 21 to 30 of about 675 (134)

NTRK expression is common in xanthogranuloma and is associated with the solitary variant

Journal of Cutaneous Pathology, Volume 50, Issue 11, Page 991-1000, November 2023., 2023
Abstract Background Previously identified mutually‐exclusive driver genes in juvenile xanthogranuloma (JXG) and adult xanthogranuloma (AXG) include mutations in MAP kinase pathway genes such as MAP2K1, BRAF, ARAF, KRAS, NRAS, PIK3CD as well as fusions in BRAF and ALK, with a subset of cases with no identified driver yet. NTRK fusion has been identified
B. Umphress, M. Kuhar, R. Kowal, A. K. Alomari, L. A. Baldridge, A. J. Ross, S. J. Warren   +6 more
wiley   +1 more source

Recalcitrant primary cutaneous Rosai‐Dorfman disease. Efficacy of sirolimus and intralesional methylprednisolone

Skin Health and Disease, Volume 3, Issue 5, October 2023., 2023
Rosai‐Dorfman disease is a sinus histiocytosis with massive lymphadenopathy. Purely‐cutaneous disease is rare. There is a lack of guidelines to treat the disease and often is based in disease severity. Abstract Sinus histiocytosis or Rosai‐Dorfman disease (RDD) is a rare disorder with severe lymphadenopathy and a limited clinical course, the aetiology ...
Andrés Tirado‐Sánchez
wiley   +1 more source

Disseminated granuloma annulare-like presentation of juvenile Wells' syndrome

Indian Journal of Paediatric Dermatology, 2017
A 5-year-old boy was referred because of urticarial flares with angioedema. Antihistamines and systemic steroids were not useful to prevent flares. At examination, at distance of a flare, chronic red-brownish plaques were found on the legs, trunk, and ...
Celestin Kouadio Ahogo, I P Gbery, B Vagamon, A Fauconneau   +3 more
doaj   +1 more source

Management Strategies for Generalised Granuloma Annulare: A Systematic Review of Current and Emerging Therapies. [PDF]

Australas J Dermatol
ABSTRACT Generalised Granuloma Annulare (GGA) is a chronic inflammatory skin disorder with no standard treatment. Since the last review in 2013, new treatments and varied responses have highlighted the need for an updated synthesis to guide clinical decisions.
Bettolini L, Maione V, Carugno A, Stabile G, Podo Brunetti A, Fratton Z, Errichetti E, Zerbinati N, Rongioletti F, Calzavara-Pinton P, Rossi M, Bighetti S.   +11 more
europepmc   +2 more sources

Therapeutic effect of dapson in six cases of Granuloma Annulare [PDF]

Journal of Kerman University of Medical Sciences, 2000
Granuloma Annulare is an flammatory bening skin disease that may manifest different clinical features.the most common presentation or classic form of the disease is fleshcolor,annulare,grouped papules,disseminated forms are rare and responses to ...
S Zandi, I Esfandyarpour
doaj  

Granuloma annulare: A rare dermatological manifestation of diabetes mellitus

Journal of Family Medicine and Primary Care, 2019
Granuloma annulare (GA) is usually a self-limited, benign granulomatous disease of the dermis and subcutaneous tissue. It's generalized or disseminated form is associated with underlying diabetes mellitus and at times it precedes the sign and symptoms of
Prabhat Agrawal, Nikhil Pursnani, Roshmy Jose, Maaz Farooqui   +3 more
doaj   +1 more source

Psychiatric adverse effects of chloroquine

Psychiatria i Psychologia Kliniczna, 2017
Chloroquine is a prototype antimalarial drug, widely used in several branches of medicine. Antimalarial drugs are used in the treatment of various dermatological, immunological, rheumatological and infectious diseases.
Anna Bogaczewicz, Tomasz Sobów
doaj   +1 more source

Cutaneous lymphomas – an update

Histopathology, EarlyView.
Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley   +1 more source

Granulomatous Dermatoses and Sarcoidosis/Sarcoid‐Like Disease During Dupilumab Therapy: A Phenotype‐Based Case‐Level Review

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Dupilumab, an interleukin‐4 receptor alpha antagonist, is widely used across Type 2 inflammatory diseases. Case reports have described granulomatous inflammation arising or worsening during treatment, but the reported phenotypes are scattered across dermatology, respiratory and allergy literature.
Mohammed Shanshal, George Karanasios, Suraiya Saleem   +2 more
wiley   +1 more source

Tattoo Exposure and Immune‐Mediated Disease: Clinical Patterns, Latency, and Mechanisms: A Systematic Review

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Tattoos are increasingly prevalent worldwide, yet links between tattoo pigment exposure and immune‐mediated disease remain incompletely defined. We performed a systematic review of MEDLINE (PubMed), Embase, and the Cochrane Library to characterize clinical phenotypes, latency, pigment features, histopathology, systemic involvement, and proposed ...
Gerardo Guilarte, Hyoungsun Park, Connor Gill, Khushnood Faraz, Miriam Motlak, Jake Breimann, Sonal Choudhary, Suraiya Saleem   +7 more
wiley   +1 more source