Results 41 to 50 of about 389 (146)

Applicability of Novel Laser Scanning Microscopy Techniques in Demonstrating Characteristic Features of Porokeratosis: In Vivo and Ex Vivo Investigation

open access: yesJEADV Clinical Practice, Volume 5, Issue 1, Page 91-100, March 2026.
Porokeratoses, used here as an example of keratinization disorders, are marked by cornoid lamella and linked to skin cancer risk, making accurate diagnosis essential. This study compared conventional methods, dermoscopy, and histopathology, with advanced imaging using reflectance confocal microscopy (RCM) and multiphoton microscopy (MPM).
Rahime Inci   +5 more
wiley   +1 more source

Efficacy and Safety of Topical Statin Therapy for Porokeratosis: A Systematic Review and Meta‐Analysis

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Background and Objective Porokeratosis comprises a heterogeneous group of keratinization disorders with malignant transformation potential. While multiple therapeutic options exist, clinical outcomes remain suboptimal. Emerging evidence suggests promising efficacy of topical statin therapy, though systematic evaluation is currently lacking.
Xingyu Li   +3 more
wiley   +1 more source

Genetic Testing in Mosaicism

open access: yesJEADV Clinical Practice, Volume 4, Issue 3, Page 664-668, August 2025.
ABSTRACT Mosaicism due to postzygotic mutations is more common than considered before the era of massive parallel sequencing. In the clinical dermatologic practice, it is important to recognize skin lesions and syndromes caused by genetic mosaicism, to initiate genetic testing and counsel the patient and families regarding prognosis and risk of ...
Cristina Has
wiley   +1 more source

Issue Information

open access: yes, 2023
JEADV Clinical Practice, Volume 2, Issue 4, Page 669-673, December 2023.
wiley   +1 more source

ISSEMINATED SUPERFICIAL ACTINIC POROKERATOSIS IN PATIENT SUFFERING FROM PLAQUE PSORIASIS: A CASE REPORT

open access: yesVestnik Dermatologii i Venerologii, 2017
Monitoring of disseminated superficial actinic porokeratosis (DSAP) in patient suffering from plaque psoriasis treated by PUVA therapy was presented. DSAP is a rare skin disease developing in the result of keratosis disorder caused by solar radiation and
L. F. Znamenskaya   +3 more
doaj   +1 more source

Disseminated superficial actinic porokeratosis

open access: yesSkin Cancer, 2003
Porokeratosis is a keratotic dermatosis which shows keratotic plaques or papular lesions, those are histologically characterized by cornoid lamella formation. It may how autosomal dominant inheritance. Disseminated superficial actinic porokeratosis (DSAP) is a type of porokeratosis which is provoked by chronic sun light exposure.
openaire   +2 more sources

Generalized type 2 segmental disseminated superficial actinic porokeratosis coexisted with multiple cutaneous squamous cell carcinomas: Analysis of two cases

open access: yesIndian Journal of Pathology and Microbiology, 2020
Porokeratosis (PK) is defined as hyperpigmented macules or patches with a distinctive, ridge-like hyperkeratotic border which is histologically characterized by a cornoid lamella.
Qiang Zhao   +6 more
doaj   +1 more source

A case of disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris

open access: yesPifu-xingbing zhenliaoxue zazhi
We report a case of disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris. A 57-year-old female presented with scattered rashes across her body for 50 years, and new rashes for 4 months.
MA Tongchuan, DONG Liping, XIAO Fengli
doaj   +1 more source

Porokeratoses: an update on pathogenesis and treatment

open access: yesInternational Journal of Dermatology, Volume 64, Issue 1, Page 62-71, January 2025.
Abstract Porokeratoses (PK) are a group of uncommon dermatoses characterized by abnormal epidermal differentiation due to a disorder of the mevalonate metabolic pathway. Several clinical subtypes exist that can be associated with the same patient or affect different patients within a family and could, therefore, be different expressions of one disease.
Konstantinos‐Antonios Kostopoulos‐Kanitakis   +1 more
wiley   +1 more source

Establishment of a Mouse Model for Porokeratosis Due to Mevalonate Diphosphate Decarboxylase Deficiency

open access: yesSkin Research and Technology, Volume 30, Issue 9, September 2024.
ABSTRACT Introduction Porokeratosis (PK) is an autoinflammatory keratinization disease (AIKD) characterized by circular or annular skin lesions with a hyperkeratotic rim, pathologically shown as the cornoid lamella. Four genes that cause PK are associated with the mevalonate (MV) pathway.
Kexin Peng   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy