Results 41 to 50 of about 389 (146)
Porokeratoses, used here as an example of keratinization disorders, are marked by cornoid lamella and linked to skin cancer risk, making accurate diagnosis essential. This study compared conventional methods, dermoscopy, and histopathology, with advanced imaging using reflectance confocal microscopy (RCM) and multiphoton microscopy (MPM).
Rahime Inci +5 more
wiley +1 more source
Background and Objective Porokeratosis comprises a heterogeneous group of keratinization disorders with malignant transformation potential. While multiple therapeutic options exist, clinical outcomes remain suboptimal. Emerging evidence suggests promising efficacy of topical statin therapy, though systematic evaluation is currently lacking.
Xingyu Li +3 more
wiley +1 more source
ABSTRACT Mosaicism due to postzygotic mutations is more common than considered before the era of massive parallel sequencing. In the clinical dermatologic practice, it is important to recognize skin lesions and syndromes caused by genetic mosaicism, to initiate genetic testing and counsel the patient and families regarding prognosis and risk of ...
Cristina Has
wiley +1 more source
Monitoring of disseminated superficial actinic porokeratosis (DSAP) in patient suffering from plaque psoriasis treated by PUVA therapy was presented. DSAP is a rare skin disease developing in the result of keratosis disorder caused by solar radiation and
L. F. Znamenskaya +3 more
doaj +1 more source
Disseminated superficial actinic porokeratosis
Porokeratosis is a keratotic dermatosis which shows keratotic plaques or papular lesions, those are histologically characterized by cornoid lamella formation. It may how autosomal dominant inheritance. Disseminated superficial actinic porokeratosis (DSAP) is a type of porokeratosis which is provoked by chronic sun light exposure.
openaire +2 more sources
Porokeratosis (PK) is defined as hyperpigmented macules or patches with a distinctive, ridge-like hyperkeratotic border which is histologically characterized by a cornoid lamella.
Qiang Zhao +6 more
doaj +1 more source
A case of disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris
We report a case of disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris. A 57-year-old female presented with scattered rashes across her body for 50 years, and new rashes for 4 months.
MA Tongchuan, DONG Liping, XIAO Fengli
doaj +1 more source
Porokeratoses: an update on pathogenesis and treatment
Abstract Porokeratoses (PK) are a group of uncommon dermatoses characterized by abnormal epidermal differentiation due to a disorder of the mevalonate metabolic pathway. Several clinical subtypes exist that can be associated with the same patient or affect different patients within a family and could, therefore, be different expressions of one disease.
Konstantinos‐Antonios Kostopoulos‐Kanitakis +1 more
wiley +1 more source
ABSTRACT Introduction Porokeratosis (PK) is an autoinflammatory keratinization disease (AIKD) characterized by circular or annular skin lesions with a hyperkeratotic rim, pathologically shown as the cornoid lamella. Four genes that cause PK are associated with the mevalonate (MV) pathway.
Kexin Peng +11 more
wiley +1 more source

