Results 11 to 20 of about 569,475 (298)

Advance care planning for adults with a progressive condition approaching end of life or loss of mental capacity: a systematic mapping review of the evidence

Health Services and Delivery Research, 2020
Background: Advance care planning (ACP) can be defined as a voluntary process of discussion about future care between an individual and their care providers, irrespective of discipline. An ACP discussion might include an individual’s concerns and wishes,
Sian Thomas, Lindsay Claxton, Kath Wright, Alison Eastwood   +3 more
doaj   +1 more source

Estimating interactions in individual participant data meta-analysis: a comparison of methods in practice

Systematic Reviews, 2022
Medical interventions may be more effective in some types of individuals than others and identifying characteristics that modify the effectiveness of an intervention is a cornerstone of precision or stratified medicine.
Ruth Walker, Lesley Stewart, Mark Simmonds   +2 more
doaj   +1 more source

Regulating and inspecting integrated health and social care in the UK: Scoping the literature

Health Services and Delivery Research, 2020
Background: The integration of care, particularly across the health and social care sectors, has been a long-standing policy objective in the UK. We sought to scope the evidence related to the regulation and inspection of integrated care.
Mark Rodgers, Gary Raine, Melissa Harden, Alison Eastwood   +3 more
doaj   +1 more source

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review

Health Technology Assessment, 2010
Objectives: To determine which class of non-opioid analgesics – paracetamol (acetaminophen), NSAIDs or COX-2 inhibitors – is the most effective at reducing morphine consumption and associated adverse effects when used as part of multimodal analgesia ...
Catriona McDaid, Emma Maund, Stephen Rice, Kath Wright, Brian Jenkins, Nerys Woolacott   +5 more
doaj   +1 more source

Pornography use and sexting amongst children and young people: a systematic overview of reviews

Systematic Reviews, 2020
Background Young people’s use of pornography and participation in sexting are commonly viewed as harmful behaviours. This paper reports findings from a ‘review of reviews’, which aimed to systematically identify and synthesise the evidence on pornography
Gary Raine, Claire Khouja, Rachel Scott, Kath Wright, Amanda J. Sowden   +4 more
doaj   +1 more source

Ablative and non-surgical therapies for early and very early hepatocellular carcinoma: a systematic review and network meta-analysis

Health Technology Assessment, 2023
Background A wide range of ablative and non-surgical therapies are available for treating small hepatocellular carcinoma in patients with very early or early-stage disease and preserved liver function. Objective To review and compare the effectiveness of
Ros Wade, Emily South, Sumayya Anwer, Sahar Sharif-Hurst, Melissa Harden, Helen Fulbright, Robert Hodgson, Sofia Dias, Mark Simmonds, Ian Rowe, Patricia Thornton, Alison Eastwood   +11 more
doaj   +1 more source

Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups

Health Technology Assessment, 2014
Background: There is currently no standard practice for the monitoring of patients receiving treatment for osteoporosis. Repeated dual-energy X-ray absorptiometry (DXA) is commonly used for monitoring treatment response, but it has its limitations.
Jane Burch, Stephen Rice, Huiqin Yang, Aileen Neilson, Lisa Stirk, Roger Francis, Paul Holloway, Peter Selby, Dawn Craig   +8 more
doaj   +1 more source

Selective internal radiation therapies for unresectable early-, intermediate- or advanced-stage hepatocellular carcinoma: systematic review, network meta-analysis and economic evaluation

Health Technology Assessment, 2020
Background: Hepatocellular carcinoma is the most common type of primary liver cancer. Treatment choice is dependent on underlying liver dysfunction and cancer stage.
Matthew Walton, Ros Wade, Lindsay Claxton, Sahar Sharif-Hurst, Melissa Harden, Jai Patel, Ian Rowe, Robert Hodgson, Alison Eastwood   +8 more
doaj   +1 more source

A systematic review of evidence for and against routine surveillance imaging after completing treatment for childhood extracranial solid tumors

Cancer Medicine, 2020
Background Regular off‐treatment imaging is often used to assess for recurrence of disease after childhood cancer treatment. It is unclear if this increases survival, or what burden surveillance places on patients, families, or health‐care services. This
Jessica E. Morgan, Ruth Walker, Melissa Harden, Robert S. Phillips   +3 more
doaj   +1 more source

Collaborative evaluation of a pilot involvement opportunity: Cochrane Common Mental Disorders Voice of Experience College

Health Expectations, 2023
Background Involving consumers in systematic reviews can make them more valuable and help achieve goals around transparency. Systematic reviews are technically complex and training can be needed to enable consumers to engage with them fully. The Cochrane
Sarah Knowles, Karen Morley, Rob Foster, Amy Middleton, Semra Pinar, Fiona Rose, Emma Williams, Jessica Hendon, Rachel Churchill   +8 more
doaj   +1 more source