Results 101 to 110 of about 177,494,970 (305)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Supplier Bottleneck and Information Dissemination
SSRN Electronic Journal, 2019 Abstract This paper investigates the capacity decisions of complementary suppliers who produce different components of a final product. The suppliers solicit private forecast information from a buyer who has more precise information regarding the market as compared to the suppliers.
Meng Li, Yue Li, Yang Zhang
openaire +2 more sources
Television information dissemination process.
, 2014 Television information dissemination process.
Jinlong Zhao (552117) +4 more
core +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Microblog information dissemination process.
, 2014 Microblog information dissemination process.
Jinlong Zhao (552117) +4 more
core +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
A study on the information seeking behaviour of Singapore-based Filipino domestic workers
, 2015 This research examines the information seeking and use behaviour of Filipino domestic workers (FDWs) in Singapore, who collectively make up around 40% of about 173,000 overseas Filipino workers (OFWs) in this city state.
Sibal, Hannah Trinity, Foo, Schubert
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Information Dissemination of Brochures and Service Encounter of Staff at Visitor Information Centres [PDF]
, 2019 Visitor Information Centres play an important role in destination tourism marketing, mainly with brochures supply and staff consults service for the visitors.
Horng Jinh Chang, Fei-Hsu Sun Hung and Yu-Wei Chung
core +1 more source