Results 31 to 40 of about 1,858 (291)

De la production à la segmentation du texte en phrases, quels outils d’analyse pour l’enseignant ?

open access: yesLidil, 2016
This article aims at identifying which analysis tolls are required to enable teachers to guide pupils when they rewrite their texts. The traditional definition of the sentence is based on four criteria which are rarely present all together in corpora ...
Marie-Laure Elalouf
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Géographes et géographie(s) à Toulouse dans les années 1970

open access: yesBulletin de l’Association de Géographes Français, 2015
The paper discusses the singular characteristic of the geography produced and taught at the university of Toulouse during the 1970s. In terms of epistemology, geographers at university of Toulouse have indeed kept their distance from the “new geography”,
Marie-Pierre Sol
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The empathic genesis of the Right to Euthanasia

open access: yesRevista Jurídica Portucalense, 2023
Euthanasia is an ancient theme that, especially since individual autonomy became the health paradigm in contemporary societies, has aroused deep reflections and declared dissensions between different socio-ideological quadrants.
Luís FONSECA   +2 more
doaj  

About »non-analytic« encounters. »Breaks«, enactments, and »dissensions« during psychotherapy as an expression of intersubjectivity

open access: yes, 2010
Im Verlauf von Psychotherapien ergeben sich gelegentlich spontane, überraschende, von dem üblichen Vorgehen abweichende Situationen.
Hanna Marx
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

« No Lady Prison didn’t improve me none ». Luttes anti-carcérales et luttes féministes après Attica

open access: yesCriminocorpus, 2019
In both the United States and France, the protest movements of the 1960s and 1970s experienced contrasting relationships, between the empowerment of spaces of struggle, agreements on the refusal of state repression, and controversies on the relationship ...
Jean Bérard
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Entre realpolitik et idéologie : la difficile route vers un nouveau traité sur le canal de Panama pendant les présidences Nixon et Ford (1969-1977)

open access: yesIdeAs
This article focuses on the negotiations for a new treaty on the Panama Canal and the Canal zone during the Nixon and Ford Administrations, prior to the final phase led with great energy by the Carter Administration.
Isabelle Vagnoux
doaj   +1 more source

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