Results 41 to 50 of about 5,620 (303)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Stefan Heym, contemporary cosmopolitan intellectual, looks back on the XVIII century
Diciottesimo Secolo, 2017 The essay considers a novel by Stefan Heym, The Queen Against Defoe, which depicts the events that took place in late 1701-early 1702 in London, when Defoe published his satirical work The Shortest Way with the Dissenters.
Marialuisa Bignami
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Acta Theologica, 2005 Although the Baptist Union of Southern Africa included relatively few outspoken critics of the apartheid system, during the 1970s and 1980s a small number of its younger members confronted the military system which supported that system of social ...
F. Hale
doaj +1 more source
, 2012 From a religiously restrictive colony controlled by the established church to an exemplar of religious freedom for a new country, Ragosta recounts Virginia’s formative struggle between the Anglican Church and dissenters, i.e., predominately Presbyterians
Pearson, Andrew
core +1 more source
Judicial Review Implementation On Dissenters Notary Rights In Making Deeds [PDF]
, 2019 The purpose of this study was to: 1) Knowing and analyzing on the Implementation of the Right Dissenters in the Making Notary Deed. 2) To determine and analyze about the obstacle Notaries in Implementing Dissenters rights.
Istiqlaly, Binta, Ma’ruf, Umar
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
“Want of Zeal for It”: Pierre Bayle on Religious Radicalization
ReligionsThis article argues that Pierre Bayle (1647–1706) is not merely a theorist of religious toleration but also a theorist of religious radicalization. By exploring how religious dissenters experienced religious conformity as a kind of mental and spiritual ...
Amy Gais
doaj +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Управленческое консультирование, 2018 The article analyzes the process of reflection of the most important religious conflict s i n English caricature at the turn of XVIII-XIX centuries: Anglo-French, anglicano-dissenters and ProtestantCatholic.
Elena Sergeevna Stetskevich +1 more
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